SCHEMBL29628844

SCHEMBL29628844

CC(C)c1cccc(C(C)C)c1N1Cc2ccccc2C1=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.54
RAB9A P51151 4/20 0.54
PKM P14618 3/20 0.53
TP53 P04637 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
KMT2A Q03164 2/20 0.50
DPP4 P27487 2/20 0.50
MEN1 O00255 1/20 0.50
LMNA P02545 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C19 P33261 1/20 0.50
NR1H2 P55055 1/20 0.50
NR1H3 Q13133 1/20 0.50
PGR P06401 1/20 0.50
CYP3A4 P08684 1/20 0.50
GAA P10253 1/20 0.50
NFKB1 P19838 1/20 0.50
DRD1 P21728 1/20 0.50
HTT P42858 1/20 0.50
NFKB2 Q00653 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23424751 0.84 NPC1 (0.54) NPC1RAB9APKMTP53SMN1; SMN2
SCHEMBL21494571 0.81 POLB (0.50) NPC1RAB9APKMSMN1; SMN2KMT2A
SCHEMBL28922624 0.79 NPC1 (0.61) NPC1RAB9APKMTP53SMN1; SMN2
SCHEMBL11301262 0.76 NPC1 (0.56) NPC1RAB9APKMTP53SMN1; SMN2
SCHEMBL6925122 0.76 DPP4 (0.58) PKMKMT2ADPP4MEN1NR1H2
SCHEMBL2739315 0.75 NPC1 (0.72) NPC1RAB9APKMTP53SMN1; SMN2
SCHEMBL9363533 0.74 NPC1 (0.49) NPC1RAB9APKMTP53SMN1; SMN2
SCHEMBL20019712 0.74 DPP4 (0.35) TP53SMN1; SMN2DPP4NR1H2NR1H3
SCHEMBL2820118 0.73 DPP4 (0.78) KMT2ADPP4NR1H2NR1H3ANPEP
SCHEMBL29366407 0.73 DPP4 (0.78) KMT2ADPP4NR1H2NR1H3ANPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11999807-B2 Particle size control of supported chromium catalysts in loop slurry polymerization reactors CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2024-06-04 US disclosed
US-20230416419-A1 PARTICLE SIZE CONTROL OF SUPPORTED CHROMIUM CATALYSTS IN LOOP SLURRY POLYMERIZATION REACTORS CHEVRON PHILLIPS CHEMICAL COMPANY LP 2023-12-28 US disclosed
US-11814449-B2 Particle size control of supported chromium catalysts in loop slurry polymerization reactors CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2023-11-14 US disclosed
EP-4259670-A2 PARTICLE SIZE CONTROL OF SUPPORTED CHROMIUM CATALYSTS IN LOOP SLURRY POLYMERIZATION REACTORS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2023-10-18 EP disclosed
US-20230121415-A1 PARTICLE SIZE CONTROL OF SUPPORTED CHROMIUM CATALYSTS IN LOOP SLURRY POLYMERIZATION REACTORS CHEVRON PHILLIPS CHEMICAL COMPANY LP 2023-04-20 US disclosed
US-11512154-B2 Particle size control of supported chromium catalysts in loop slurry polymerization reactors CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2022-11-29 US disclosed
US-20220227897-A1 PARTICLE SIZE CONTROL OF SUPPORTED CHROMIUM CATALYSTS IN LOOP SLURRY POLYMERIZATION REACTORS CHEVRON PHILLIPS CHEMICAL COMPANY LP 2022-07-21 US disclosed
WO-2022125581-A2 PARTICLE SIZE CONTROL OF SUPPORTED CHROMIUM CATALYSTS IN LOOP SLURRY POLYMERIZATION REACTORS CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2022-06-16 WO disclosed
US-11325997-B1 Particle size control of supported chromium catalysts in loop slurry polymerization reactors CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2022-05-10 US disclosed