Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 7/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.57 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11603313 | 0.84 | GRIK1 (0.62) | GRIK1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL11113166 | 0.84 | AKR1C3 (0.79) | GRIK1MEN1KMT2AMAPTAKR1C3 | |
| SCHEMBL11604096 | 0.81 | KDM4E (0.60) | GRIK1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL28958576 | 0.81 | GRIK1 (0.62) | GRIK1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL21346876 | 0.80 | GAK (0.60) | ALDH1A1KDM4EMAPTUSP2SMN1; SMN2 | |
| SCHEMBL8390616 | 0.80 | KDM4E (0.53) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL4858020 | 0.79 | GRIK1 (0.51) | GRIK1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL11604086 | 0.78 | CLCN2 (0.61) | GRIK1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL10834344 | 0.78 | AKR1C3 (0.84) | GRIK1MEN1KMT2AMAPTUSP2 | |
| SCHEMBL11606483 | 0.78 | PPARG (0.64) | GRIK1ALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57123152-A | — | — | None | — | — | JP | disclosed |
| JP-S57123152-A | NOVEL AMINOBENZOIC ACID DERIVATIVE AND DRUG COMPOSITION | CHUGAI PHARMACEUT CO LTD | 1982-07-31 | — | — | JP | disclosed |