Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.55 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.55 |
| ▸ | CLCN2 | P51788 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | FABP3 | P05413 | 1/20 | 0.49 |
| ▸ | FABP4 | P15090 | 1/20 | 0.49 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TRPM4 | Q8TD43 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CCR2 | P41597 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28965118 | 0.85 | G6PD (0.55) | GRIK1MEN1KMT2AAKR1C3AKR1C2 | |
| SCHEMBL30058623 | 0.85 | G6PD (0.55) | GRIK1MEN1KMT2AAKR1C3AKR1C2 | |
| SCHEMBL13271379 | 0.83 | FABP3 (0.68) | MEN1KMT2AAKR1C3AKR1C2CLCN2 | |
| SCHEMBL11605493 | 0.82 | ACLY (0.54) | GRIK1MEN1KMT2AUSP2PABPC1 | |
| SCHEMBL11301337 | 0.81 | GRIK1 (0.60) | GRIK1MEN1KMT2AUSP2PABPC1 | |
| SCHEMBL7568128 | 0.80 | MEN1 (0.51) | GRIK1MEN1KMT2AUSP2PABPC1 | |
| SCHEMBL1308706 | 0.79 | KCNMA1 (0.74) | GRIK1MEN1KMT2AUSP2KDM4E | |
| SCHEMBL28404353 | 0.79 | AKR1C3 (0.81) | GRIK1MEN1KMT2AUSP2PABPC1 | |
| SCHEMBL1463298 | 0.76 | GRIK1 (1.00) | GRIK1MEN1KMT2AKDM4EGAA | |
| SCHEMBL11113166 | 0.76 | AKR1C3 (0.79) | GRIK1MEN1KMT2AAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115557890-B | Polysubstituted acridone alkyl derivative and preparation method and application thereof | 宁波大学 | 2024-06-25 | — | — | CN | disclosed |
| CN-115557890-A | Polysubstituted acridone alkyl derivative and preparation method and application thereof | 宁波大学 | 2023-01-03 | — | — | CN | disclosed |