SCHEMBL11301428

SCHEMBL11301428

CCCC(c1c(C)n(C)n(-c2ccccc2)c1=O)c1c(C)n(C)n(-c2ccccc2)c1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 1.00
MEN1 O00255 5/20 0.82
KMT2A Q03164 5/20 0.82
NPSR1 Q6W5P4 1/20 0.82
LMNA P02545 2/20 0.69
ADORA3 P0DMS8 1/20 0.69
MAPT P10636 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.56
KDM4E B2RXH2 1/20 0.55
CYP1A2 P05177 1/20 0.55
CYP2D6 P10635 1/20 0.55
ALDH1A1 P00352 3/20 0.54
GAA P10253 1/20 0.54
PTGS2 P35354 2/20 0.54
BCHE P06276 1/20 0.54
ALOX15 P16050 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11301853 0.90 MEN1 (1.00) POLBMEN1KMT2ANPSR1LMNA
SCHEMBL11303716 0.85 POLB (0.74) POLBMEN1KMT2ANPSR1LMNA
SCHEMBL11319112 0.84 LMNA (0.73) POLBMEN1KMT2ANPSR1LMNA
SCHEMBL18084405 0.83 LMNA (0.71) POLBMEN1KMT2ANPSR1LMNA
SCHEMBL11313942 0.82 LMNA (0.81) POLBMEN1KMT2ANPSR1LMNA
Propyphenazone SCHEMBL23393 0.82 LMNA (1.00) POLBMEN1KMT2ANPSR1LMNA
SCHEMBL11306629 0.82 LMNA (0.81) POLBMEN1KMT2ANPSR1LMNA
Propyphenazone SCHEMBL7929540 0.81 LMNA (0.97) POLBMEN1KMT2ANPSR1LMNA
SCHEMBL28824167 0.80 LMNA (0.76) POLBMEN1KMT2ANPSR1LMNA
SCHEMBL28143511 0.79 LMNA (0.69) POLBMEN1KMT2ANPSR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118326169-A Separation from Zn irradiation target67Cu method and device 西安迈斯拓扑科技有限公司 2024-07-12 CN disclosed
US-4315068-A CONTAINING A COBALT-AMMINE COMPLEX AND A DIOXIME OR A BISIMIDAZOLIN-3-ONE CHELATING AGENT; STABILITY; COLOR DILMS RICOH CO., LTD. (JP) 1982-02-09 US disclosed