Propyphenazone

Propyphenazone

SCHEMBL23393

Cc1c(C(C)C)c(=O)n(-c2ccccc2)n1C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 1.00
ADORA3 P0DMS8 1/20 1.00
POLB P06746 1/20 0.69
PTGS2 P35354 2/20 0.64
MEN1 O00255 5/20 0.64
KMT2A Q03164 5/20 0.64
MAPT P10636 1/20 0.64
NPSR1 Q6W5P4 1/20 0.64
SMN1; SMN2 Q16637 1/20 0.62
KDM4E B2RXH2 1/20 0.62
CYP1A2 P05177 1/20 0.62
CYP2D6 P10635 1/20 0.62
ALDH1A1 P00352 3/20 0.62
BCHE P06276 1/20 0.62
ALOX15 P16050 1/20 0.62
NPC1 O15118 1/20 0.61
HTT P42858 1/20 0.61
GAA P10253 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propyphenazone SCHEMBL7929540 0.98 LMNA (0.97) LMNAADORA3POLBPTGS2MEN1
SCHEMBL11306629 0.89 LMNA (0.81) LMNAADORA3POLBPTGS2MEN1
SCHEMBL11313942 0.89 LMNA (0.81) LMNAADORA3POLBPTGS2MEN1
Propyphenazone SCHEMBL28086369 0.88 LMNA (0.81) LMNAADORA3POLBPTGS2MEN1
SCHEMBL28824167 0.86 LMNA (0.76) LMNAADORA3POLBPTGS2MEN1
SCHEMBL6720188 0.85 MEN1 (0.81) LMNAADORA3POLBMEN1KMT2A
SCHEMBL11319112 0.85 LMNA (0.73) LMNAADORA3POLBPTGS2MEN1
Propyphenazone SCHEMBL27899010 0.84 LMNA (0.70) LMNAADORA3POLBPTGS2MEN1
SCHEMBL18084405 0.83 LMNA (0.71) LMNAADORA3POLBPTGS2MEN1
SCHEMBL15614523 0.83 LMNA (0.71) LMNAADORA3POLBPTGS2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4418 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260083666-A1 METHOD OF TREATING DISEASE CREWS THOMAS M (US) 2026-03-26 US claimed
EP-4679085-A1 BIOMARKER AND USE THEREOF MEIJI CO., LTD (JP) 2026-01-14 EP claimed
US-20250255781-A1 PROCESSES FOR PREPARATION OF 3-D PRINTED PHARMACEUTICAL PRODUCTS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-08-14 US claimed
US-12296043-B2 Liquisoft capsules PATHEON SOFTGELS INC. (US) 2025-05-13 US claimed
EP-4510999-A1 PROCESSES FOR PREPARATION OF 3-D PRINTED PHARMACEUTICAL PRODUCTS Bristol-Myers Squibb Company (US) 2025-02-26 EP claimed
US-20250058025-A1 A THREE-DIMENSIONAL BIOCOMPATIBLE MATRIX AND ITS USES IN WOUND MANAGEMENT AXENOLL LIFE SCIENCES AG (CH) 2025-02-20 US claimed
CN-119303086-A Pharmaceutical composition for treating autism 斯塔利克拉股份有限公司 2025-01-14 CN claimed
EP-4452349-A1 A THREE-DIMENSIONAL BIOCOMPATIBLE MATRIX AND ITS USES IN WOUND MANAGEMENT Axenoll Life Sciences AG (CH) 2024-10-30 EP claimed
WO-2024190666-A1 BIOMARKER AND USE THEREOF 株式会社明治 2024-09-19 WO claimed
US-20240269115-A1 PYRAZOLONE COMPOUNDS FOR USE IN DEGENERATIVE RETINAL DISEASES FLONEXT S.R.L. (IT) 2024-08-15 US claimed
EP-0792371-A1 COMBINATION METHOD FOR ACNE TREATMENT Merck & Co., Inc. (US) 1997-09-03 EP claimed
EP-0786999-A1 COMBINATION METHOD FOR ACNE TREATMENT Merck & Co., Inc. (US) 1997-08-06 EP claimed
CN-1142766-A Antipyretic analgesic combination medicament FUJIZAWA PHARMACEUTICAL CO LTD (JP) 1997-02-12 CN claimed
US-5543417-A 5 Alpha-reductase inhibitor and at least one of an antibacterial agent, a keratolytic agent or an anti-inflammatory agent MERCK & CO., INC. (US) 1996-08-06 US claimed
WO-1996012487-A1 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO., INC. (US) 1996-05-02 WO claimed
WO-1996012817-A1 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO., INC. (US) 1996-05-02 WO claimed
EP-0272638-B1 ANALGESIC PREPARATION F. HOFFMANN-LA ROCHE AG (CH) 1992-05-20 EP claimed
US-4540602-A Process for the preparation of activated pharmaceutical compositions FREUND INDUSTRY COMPANY, LIMITED (JP) 1985-09-10 US claimed
EP-0007572-B1 PHARMACEUTICAL MIXTURES CONTAINING AN AMANTADINE COMPOUND CIBA-GEIGY AG (CH) 1983-04-27 EP claimed
US-4181719-A Analgesic N-acetyl-para-aminophenyl N'-acetylaminothioalkanoates STERLING DRUG INC. (US) 1980-01-01 US claimed