SCHEMBL11301729

SCHEMBL11301729

CC/C=C(\CCC)C(N)=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 1/20 0.39
GRIK2 Q13002 1/20 0.39
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
HDAC3 O15379 4/20 0.36
HDAC1 Q13547 4/20 0.36
HDAC2 Q92769 4/20 0.36
HDAC8 Q9BY41 4/20 0.36
FFAR3 O14843 3/20 0.36
CTSD P07339 1/20 0.36
TSHR P16473 1/20 0.35
FAAH O00519 3/20 0.34
SOAT1 P35610 2/20 0.33
ALDH1A1 P00352 1/20 0.33
MEN1 O00255 1/20 0.33
TP53 P04637 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11288814 1.00 GRIK1 (0.39) GRIK1GRIK2CES2CES1HDAC3
SCHEMBL11288817 1.00 GRIK1 (0.39) GRIK1GRIK2CES2CES1HDAC3
SCHEMBL4742990 0.86 CES1 (0.42) GRIK1GRIK2CES2CES1FAAH
SCHEMBL6113439 0.84 GRIK1 (0.38) GRIK1GRIK2
SCHEMBL570952 0.84 GRIK1 (0.44) GRIK1GRIK2CES2CES1HDAC3
SCHEMBL541990 0.84 GRIK1 (0.44) GRIK1GRIK2CES2CES1HDAC3
SCHEMBL28586743 0.84 CES2 (0.36) CES2CES1HDAC3HDAC1HDAC2
SCHEMBL2483445 0.83 FAAH (0.50) CES2CES1TSHRFAAHSOAT1
SCHEMBL30777646 0.83 FAAH (0.50) CES2CES1TSHRFAAHSOAT1
SCHEMBL27887497 0.82 FAAH (0.39) GRIK1GRIK2FAAHSOAT1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2697193-A1 SUBSTITUTED 5-(CYCLOHEX-2-EN-1-YL)-PENTA-2,4-DIENES AND 5-(CYCLOHEX-2-EN-1-YL)-PENT-2-EN-4-INES AS ACTIVE AGENTS AGAINST ABIOTIC STRESS IN PLANTS Bayer Intellectual Property GmbH (DE) 2014-02-19 EP disclosed
WO-2012139890-A1 SUBSTITUTED 5-(CYCLOHEX-2-EN-1-YL)-PENTA-2,4-DIENES AND 5-(CYCLOHEX-2-EN-1-YL)-PENT-2-EN-4-INES AS ACTIVE AGENTS AGAINST ABIOTIC STRESS IN PLANTS BAYER CROPSCIENCE AG (DE) 2012-10-18 WO disclosed
EP-0024682-B1 PROCESS FOR THE PREPARATION OF N-PROPYL-N-PROPYLIDENE ACETAMIDE OR DI-N-PROPYL ACETAMIDE Consortium für elektrochemische Industrie GmbH (DE) 1982-12-22 EP disclosed
EP-0024682-A1 Process for the preparation of n-propyl-n-propylidene acetamide or di-n-propyl acetamide Consortium für elektrochemische Industrie GmbH (DE) 1981-03-11 EP disclosed