Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.66 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.51 |
| ▸ | HTR2B | P41595 | 2/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | MLNR | O43193 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL276735 | 0.98 | LTA4H (0.68) | LTA4HNR1I2CHRM2ADRA2AOPRK1 | |
| SCHEMBL6933945 | 0.89 | LMNA (0.57) | LTA4HNR1I2CHRM2ADRA2AOPRK1 | |
| SCHEMBL28300288 | 0.87 | LTA4H (0.55) | LTA4HMEN1MAPTKMT2ASLC6A2 | |
| SCHEMBL19612247 | 0.87 | LTA4H (0.58) | LTA4HNR1I2CHRM2ADRA2AOPRK1 | |
| SCHEMBL2859001 | 0.87 | LMNA (0.62) | LTA4HNR1I2CHRM2ADRA2AOPRK1 | |
| SCHEMBL2245919 | 0.87 | LMNA (0.62) | LTA4HNR1I2CHRM2ADRA2AOPRK1 | |
| SCHEMBL1964196 | 0.87 | LMNA (0.62) | LTA4HNR1I2CHRM2ADRA2AOPRK1 | |
| SCHEMBL9387360 | 0.87 | LMNA (0.62) | LTA4HNR1I2CHRM2ADRA2AOPRK1 | |
| SCHEMBL9394792 | 0.87 | LMNA (0.62) | LTA4HNR1I2CHRM2ADRA2AOPRK1 | |
| SCHEMBL30620186 | 0.87 | LMNA (0.62) | LTA4HNR1I2CHRM2ADRA2AOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4278816-A | FROM DIPHENYL ETHERS AND HYDROGEN SULFIDE, ABSORPTIVE CATALYST | STAUFFER CHEMICAL COMPANY (US) | 1981-07-14 | — | — | US | disclosed |