Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11301936 | 1.00 | TSHR (0.44) | TSHRPIK3CACA2DHODHKMT2A | |
| SCHEMBL11297353 | 0.83 | ALDH1A1 (0.43) | TSHRPIK3CAKMT2AMAOBHTT | |
| SCHEMBL11297351 | 0.83 | ALDH1A1 (0.43) | TSHRPIK3CAKMT2AMAOBHTT | |
| SCHEMBL11298312 | 0.82 | ALDH1A1 (0.42) | TSHRPIK3CAKMT2AMAOBHTT | |
| SCHEMBL11298311 | 0.82 | ALDH1A1 (0.42) | TSHRPIK3CAKMT2AMAOBHTT | |
| SCHEMBL11303482 | 0.81 | CTBP2 (0.49) | PIK3CADHODHKMT2AMAOBHTT | |
| SCHEMBL11303480 | 0.81 | CTBP2 (0.49) | PIK3CADHODHKMT2AMAOBHTT | |
| SCHEMBL11301348 | 0.77 | TP53 (0.43) | KMT2AMAOBHTTSMN1; SMN2 | |
| SCHEMBL11301345 | 0.77 | TP53 (0.43) | KMT2AMAOBHTTSMN1; SMN2 | |
| SCHEMBL11305682 | 0.76 | AKR1B1 (0.51) | DHODHKMT2AMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4254048-A | ANTIINFLAMMATORY AGENTS; FOR ARTHRITIS | AMERICAN CYANAMID COMPANY (US) | 1981-03-03 | — | — | US | claimed |