Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11301345 | 1.00 | TP53 (0.43) | TP53MAPK10CTBP2TDP1POLB | |
| SCHEMBL11297351 | 0.84 | ALDH1A1 (0.43) | CTBP2TDP1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL11297353 | 0.84 | ALDH1A1 (0.43) | CTBP2TDP1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL11298311 | 0.83 | ALDH1A1 (0.42) | CTBP2TDP1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL11298312 | 0.83 | ALDH1A1 (0.42) | CTBP2TDP1SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL11299981 | 0.82 | MAOB (0.46) | MAPK10GAARAB9AKMT2AKDM4E | |
| SCHEMBL11299966 | 0.82 | MAOB (0.46) | MAPK10GAARAB9AKMT2AKDM4E | |
| SCHEMBL11301938 | 0.77 | TSHR (0.44) | SMN1; SMN2HTTKMT2AMAOB | |
| SCHEMBL11301936 | 0.77 | TSHR (0.44) | SMN1; SMN2HTTKMT2AMAOB | |
| SCHEMBL11298293 | 0.75 | ALDH1A1 (0.46) | GAASMN1; SMN2ALDH1A1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4254048-A | ANTIINFLAMMATORY AGENTS; FOR ARTHRITIS | AMERICAN CYANAMID COMPANY (US) | 1981-03-03 | — | — | US | claimed |