Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 7/20 | 0.48 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.45 |
| ▸ | TLR2 | O60603 | 8/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.42 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11302035 | 1.00 | PLA2G2A (0.48) | PLA2G2APLA2G10TLR2LPAR1LPAR3 | |
| Hydrochloric Acid SCHEMBL11308092 | 0.99 | PLA2G2A (0.47) | PLA2G2APLA2G10TLR2LPAR1LPAR3 | |
| SCHEMBL11299159 | 0.92 | HTT (0.41) | PLA2G2APLA2G10TLR2LPAR1LPAR3 | |
| SCHEMBL13997509 | 0.84 | PLA2G10 (0.55) | PLA2G2APLA2G10TLR2LPAR1LPAR3 | |
| SCHEMBL4368865 | 0.84 | PLA2G10 (0.55) | PLA2G2APLA2G10TLR2LPAR1LPAR3 | |
| SCHEMBL25078776 | 0.84 | PLA2G10 (0.55) | PLA2G2APLA2G10TLR2LPAR1LPAR3 | |
| SCHEMBL3762356 | 0.84 | PLA2G10 (0.55) | PLA2G2APLA2G10TLR2LPAR1LPAR3 | |
| SCHEMBL2411920 | 0.84 | PLA2G10 (0.55) | PLA2G2APLA2G10TLR2LPAR1LPAR3 | |
| SCHEMBL25078765 | 0.84 | PLA2G10 (0.55) | PLA2G2APLA2G10TLR2LPAR1LPAR3 | |
| SCHEMBL2411902 | 0.84 | PLA2G10 (0.55) | PLA2G2APLA2G10TLR2LPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4262021-A | INDUCERS OF PRODUCTION OF INTERFERON | PFIZER INC. (US) | 1981-04-14 | — | — | US | disclosed |
| US-4215146-A | Antiviral amine derivatives of glycerol and propanediols | PFIZER INC. (US) | 1980-07-29 | — | — | US | disclosed |
| US-4193999-A | Antiviral amine derivatives of propanediols | PFIZER INC. (US) | 1980-03-18 | — | — | US | disclosed |