Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 4/20 | 0.50 |
| ▸ | HTR1B | P28222 | 2/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 7/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3034603 | 0.83 | RHEB (0.45) | RHEBHTR1BTRPA1HTR1AAHR | |
| SCHEMBL29992666 | 0.83 | RHEB (0.45) | RHEBHTR1BTRPA1HTR1AAHR | |
| SCHEMBL2087774 | 0.81 | HTR1B (0.51) | RHEBHTR1BTRPA1HTR1AAHR | |
| SCHEMBL30681623 | 0.80 | AHR (0.57) | RHEBHTR1BTRPA1HTR1AAHR | |
| SCHEMBL29992707 | 0.79 | RHEB (0.54) | RHEBHTR1BTRPA1HTR1AAHR | |
| SCHEMBL321761 | 0.79 | RHEB (0.54) | RHEBHTR1BTRPA1HTR1AAHR | |
| SCHEMBL29445066 | 0.79 | RHEB (0.54) | RHEBHTR1BTRPA1HTR1AAHR | |
| SCHEMBL1499400 | 0.78 | RHEB (0.73) | RHEBHTR1BTRPA1HTR1AAHR | |
| Ethane SCHEMBL7616752 | 0.77 | RHEB (0.53) | RHEBHTR1BTRPA1HTR1AAHR | |
| Ethyne SCHEMBL28266951 | 0.76 | RHEB (0.51) | RHEBHTR1BTRPA1HTR1AAHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56140970-A | — | — | None | — | — | JP | disclosed |
| JP-56167668-A | — | — | None | — | — | JP | disclosed |
| JP-S56167668-A | PREPARATION OF INDOLE DERIVATIVE | RONZA CHEM:KK | 1981-12-23 | — | — | JP | disclosed |
| JP-S56140970-A | PREPARATION OF INDOLE DERIVATIVE | RONZA CHEM:KK | 1981-11-04 | — | — | JP | disclosed |