Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 3/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CHAT | P28329 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cinnamonitrile SCHEMBL996307 | 0.95 | KDM4E (0.54) | KDM4EMAOBNFE2L2CYP19A1MAOA | |
| Cinnamonitrile SCHEMBL23599 | 0.95 | KDM4E (0.54) | KDM4EMAOBNFE2L2CYP19A1MAOA | |
| Cinnamonitrile SCHEMBL23933 | 0.95 | KDM4E (0.54) | KDM4EMAOBNFE2L2CYP19A1MAOA | |
| SCHEMBL10846493 | 0.90 | KDM4E (0.64) | KDM4EMAOBNFE2L2CYP19A1MAOA | |
| SCHEMBL3144474 | 0.90 | KDM4E (0.64) | KDM4EMAOBNFE2L2CYP19A1MAOA | |
| Cinnamonitrile SCHEMBL28165460 | 0.86 | ENPP2 (0.50) | KDM4EMAOBNFE2L2CYP19A1MAOA | |
| SCHEMBL1287794 | 0.86 | KDM4E (0.52) | KDM4EMAOBNFE2L2CYP19A1MAOA | |
| SCHEMBL11265587 | 0.86 | KDM4E (0.52) | KDM4EMAOBNFE2L2CYP19A1MAOA | |
| Cinnamonitrile SCHEMBL28064832 | 0.86 | KDM4E (0.47) | KDM4EMAOBNFE2L2CYP19A1MAOA | |
| Cinnamonitrile SCHEMBL27473675 | 0.86 | KDM4E (0.62) | KDM4EMAOBNFE2L2CYP19A1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0062608-A1 | 4-Halogenostilbene derivatives and process for their preparation | CIBA-GEIGY AG (CH) | 1982-10-13 | — | — | EP | disclosed |