Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1287794 | 1.00 | KDM4E (0.52) | KDM4ECA1MGLLHDAC2HDAC1 | |
| Cinnamonitrile SCHEMBL28165460 | 0.91 | ENPP2 (0.50) | KDM4ECA1MGLLHDAC2HDAC1 | |
| SCHEMBL11125760 | 0.91 | KDM4E (0.59) | KDM4ECA1MGLLHDAC2HDAC1 | |
| SCHEMBL11304576 | 0.86 | KDM4E (0.55) | KDM4EHDAC1ENPP2MAOBNFE2L2 | |
| Cinnamonitrile SCHEMBL23599 | 0.86 | KDM4E (0.54) | KDM4ECA1HDAC2HDAC1HDAC6 | |
| Cinnamonitrile SCHEMBL996307 | 0.86 | KDM4E (0.54) | KDM4ECA1HDAC2HDAC1HDAC6 | |
| Cinnamonitrile SCHEMBL23933 | 0.86 | KDM4E (0.54) | KDM4ECA1HDAC2HDAC1HDAC6 | |
| SCHEMBL8904305 | 0.82 | ENPP2 (0.54) | KDM4EHDAC2HDAC1HDAC6ENPP2 | |
| SCHEMBL8904307 | 0.82 | ENPP2 (0.54) | KDM4EHDAC2HDAC1HDAC6ENPP2 | |
| SCHEMBL11293055 | 0.81 | KDM4E (0.43) | KDM4ECA1MGLLHDAC2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111606824-B | Beta-amino nitrile compound and preparation method thereof | 东北师范大学 | 2023-03-14 | — | — | CN | claimed |
| CN-111606824-A | Beta-amino nitrile compound and preparation method thereof | 东北师范大学 | 2020-09-01 | — | — | CN | claimed |
| US-20230142654-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF | PIMEDBIO, INC. (KR) | 2023-05-11 | — | — | US | disclosed |
| US-20230142654-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF | PIMEDBIO, INC. (KR) | 2023-05-11 | — | — | US | disclosed |
| CN-111606824-B | Beta-amino nitrile compound and preparation method thereof | 东北师范大学 | 2023-03-14 | — | — | CN | disclosed |
| EP-3625218-B1 | PROCESS FOR HYDROCYANATION OF TERMINAL ALKYNES | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2023-03-01 | — | — | EP | disclosed |
| EP-3625218-B1 | PROCESS FOR HYDROCYANATION OF TERMINAL ALKYNES | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2023-03-01 | — | — | EP | disclosed |
| WO-2021145729-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF | DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION (KR) | 2021-07-22 | — | — | WO | disclosed |
| US-10947186-B2 | Process for hydrocyanation of terminal alkynes | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2021-03-16 | — | — | US | disclosed |
| US-10947186-B2 | Process for hydrocyanation of terminal alkynes | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2021-03-16 | — | — | US | disclosed |
| CN-111606824-A | Beta-amino nitrile compound and preparation method thereof | 东北师范大学 | 2020-09-01 | — | — | CN | disclosed |
| US-20200181068-A1 | PROCESS FOR HYDROCYANATION OF TERMINAL ALKYNES | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2020-06-11 | — | — | US | disclosed |
| US-20200181068-A1 | PROCESS FOR HYDROCYANATION OF TERMINAL ALKYNES | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2020-06-11 | — | — | US | disclosed |
| US-4336264-A | 1-Benzoyl-3-(isoxazolyl or benzisoxazolyl)-ureas and insecticidal use thereof | ELI LILLY AND COMPANY (US) | 1982-06-22 | — | — | US | disclosed |
| US-4335054-A | Process for the preparation of alkenylbenzenecarboxylic acid derivatives and alkenylnaphthalenecarboxylic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1982-06-15 | — | — | US | disclosed |
| US-4322429-A | Isoxazolylbenzamides as insecticides | ELI LILLY AND COMPANY (US) | 1982-03-30 | — | — | US | disclosed |
| EP-0048162-A1 | Isoxazolylbenzamides | ELI LILLY AND COMPANY (US) | 1982-03-24 | — | — | EP | disclosed |
| EP-0042732-A1 | 1-benzoyl-3-substituted ureas and thioureas, their preparation, insecticidal formulations containing them and their use as insecticides | ELI LILLY AND COMPANY (US) | 1981-12-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200181068-A1 | PROCESS FOR HYDROCYANATION OF TERMINAL ALKYNES | ALKBH3, ALKBH2, ALKBH5 | KDM4E 154/4885CA1 3595/4885MGLL 1995/4885 |
| US-20230142654-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF | TYR, TYRO3, TH | KDM4E 619/4885CA1 2779/4885MGLL 2997/4885 |
| US-10947186-B2 | Process for hydrocyanation of terminal alkynes | ALKBH3, ALKBH2, ALKBH5 | KDM4E 154/4885CA1 3595/4885MGLL 1995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.