SCHEMBL113047

SCHEMBL113047

CC(C)c1cccc(C(C)C)c1NCNc1c(C(C)C)cccc1C(C)C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.48
GABRA1 P14867 3/20 0.46
GABRG2 P18507 2/20 0.46
GABRB3 P28472 2/20 0.46
LMNA P02545 2/20 0.46
GABRB2 P47870 2/20 0.46
FAAH O00519 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
HPGD P15428 1/20 0.46
TSHR P16473 1/20 0.46
GABRB1 P18505 1/20 0.46
PTGS1 P23219 1/20 0.46
SLC6A2 P23975 1/20 0.46
HTR2C P28335 1/20 0.46
GABRA5 P31644 1/20 0.46
GABRA3 P34903 1/20 0.46
HTR2B P41595 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL114632 0.87 MAPK1 (0.49) SMN1; SMN2GABRA1GABRG2GABRB3LMNA
SCHEMBL29464080 0.87 MAPK1 (0.49) SMN1; SMN2GABRA1GABRG2GABRB3LMNA
SCHEMBL10390549 0.87 HTT (0.44) SMN1; SMN2GABRA1GABRG2GABRB3LMNA
SCHEMBL2520538 0.86 SMN1; SMN2 (0.53) SMN1; SMN2GABRA1GABRG2GABRB3LMNA
SCHEMBL11107355 0.84 SMN1; SMN2 (0.47) SMN1; SMN2GABRA1GABRG2GABRB3LMNA
SCHEMBL30358476 0.82 GABRA1 (0.34) SMN1; SMN2GABRA1GABRG2GABRB3LMNA
SCHEMBL5839357 0.82 SMN1; SMN2 (0.50) SMN1; SMN2GABRA1GABRG2GABRB3LMNA
SCHEMBL10630412 0.82 SMN1; SMN2 (0.50) SMN1; SMN2GABRA1GABRG2GABRB3LMNA
SCHEMBL5838666 0.82 SMN1; SMN2 (0.50) SMN1; SMN2GABRA1GABRG2GABRB3LMNA
SCHEMBL5839450 0.80 SMN1; SMN2 (0.44) SMN1; SMN2GABRA1GABRG2GABRB3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11535686-B2 Tough, high temperature polymers produced by stereolithography CARBON, INC. (US) 2022-12-27 US claimed
CN-115244096-A Curable polyurethane prepolymer compositions 朗盛公司 2022-10-25 CN claimed
EP-3441411-B1 POLYURETHANE SYSTEM AND ITS USE IN PRINTING TECHNOLOGY RAMPF POLYMER SOLUTIONS GMBH & CO KG (DE) 2022-02-09 EP claimed
EP-3441411-A1 POLYURETHANE SYSTEM AND ITS USE IN PRINTING TECHNOLOGY RAMPF Holding GmbH & Co. KG (DE) 2019-02-13 EP claimed
EP-3441410-A1 POLYURETHANE SYSTEM AND ITS USE IN PRINTING TECHNOLOGY RAMPF Holding GmbH & Co. KG (DE) 2019-02-13 EP claimed
US-8779036-B2 Catalysis of epoxy resin formulations EVONIK DEGUSSA GMBH (DE) 2014-07-15 US claimed
EP-2456804-A1 CATALYSIS OF EPOXY RESIN FORMULATIONS HAVING SPARINGLY SOLUBLE CATALYSTS Evonik Degussa GmbH (DE) 2012-05-30 EP claimed
US-20120115988-A1 CATALYSIS OF EPOXY RESIN FORMULATIONS HAVING SPARINGLY SOLUBLE CATALYSTS EVONIK DEGUSSA GMBH (DE) 2012-05-10 US claimed
EP-2424916-A1 CATALYSIS OF EPOXY RESIN FORMULATIONS Evonik Degussa GmbH (DE) 2012-03-07 EP claimed
US-20120041101-A1 CATALYSIS OF EPOXY RESIN FORMULATIONS EVONIK DEGUSSA GMBH (DE) 2012-02-16 US claimed
EP-0424076-B1 Chemorheologically tailored matrix resin formulations and their use in making pre-impregnated fibers and in fabricating composite parts THIOKOL CORP (US) 1995-12-20 EP claimed
US-5356499-A Method for increasing fiber strength translation in composite pressure vessels using matrix resin formulations containing surface acting agents THIOKOL CORPORATION (US) 1994-10-18 US claimed
US-5011721-A Controlling viscosity THIOKOL CORPORATION (US) 1991-04-30 US claimed
US-4978791-A CROSSLINKING OR CHAIN EXTENSION AGENTS FOR POLYURETHANES OR EPOXY RESINS LONZA LTD. (CH) 1990-12-18 US claimed
EP-0122149-B1 METAL FLUOBORATE CATALYSED HINDERED AROMATIC AMINO CURING AGENTS FOR POLYEPOXIDE RESINS INTEREZ, Inc. (a Georgia corporation) (US) 1988-07-06 EP claimed
EP-0120666-B1 POLYGLYCIDYL HINDERED AROMATIC AMINES INTEREZ, Inc. (a Georgia corporation) (US) 1987-07-08 EP claimed
US-4526905-A Chain extenders ETHYL CORPORATION (US) 1985-07-02 US claimed
US-4487948-A POLYEPOXIDES, HEAT RESISTANCE, STORAGE STABILITY CELANESE CORPORATION (US) 1984-12-11 US claimed
US-4447586-A Metal fluoborate catalyzed hindered aromatic amine curing agents for polyepoxide resins CELANESE CORPORATION (US) 1984-05-08 US claimed
US-4267299-A BY ADDITION OF POLYOL OR POLYAMINE CURING AGENTS AND REACTIVE POLYOL FILLERS METALWELD, INC. (US) 1981-05-12 US claimed