Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6348838 | 0.78 | TRPA1 (0.46) | CA2MAPTRAB9AALDH1A1TSHR | |
| SCHEMBL20349303 | 0.78 | TSHR (0.38) | CA2CA1CA4CA6TSHR | |
| SCHEMBL715475 | 0.76 | GAA (0.48) | CA2CA1CA4CA6CYP3A4 | |
| SCHEMBL723523 | 0.76 | GAA (0.54) | CA2CA1CA4CA6CYP3A4 | |
| SCHEMBL8515024 | 0.74 | GAA (0.47) | CA2CA1CA4CA6CYP3A4 | |
| SCHEMBL24423317 | 0.71 | ESR1 (0.48) | CA2CA1CA4CA6CYP3A4 | |
| SCHEMBL5338751 | 0.71 | GAA (0.55) | CA2MEN1KMT2AGAAMAPT | |
| SCHEMBL992274 | 0.69 | CALM1 (0.50) | CYP3A4MEN1KMT2AIDH1CALM1 | |
| SCHEMBL30407861 | 0.69 | KLKB1 (0.62) | GAAMAPTKDM4EALDH1A1TSHR | |
| SCHEMBL10539851 | 0.68 | CYP3A4 (0.45) | CA2CA1CA4CA6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4293406-A | Synergistic promoter combination for zinc sulfide ores | AMERICAN CYANAMID COMPANY (US) | 1981-10-06 | — | — | US | disclosed |