Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 4/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11323151 | 0.80 | TP53 (0.45) | ALDH1A1HPGDHSD17B10PARP1TP53 | |
| SCHEMBL11308974 | 0.80 | ALDH1A1 (0.48) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL11313624 | 0.78 | SIGMAR1 (0.50) | SIGMAR1 | |
| SCHEMBL11319923 | 0.77 | PADI4 (0.42) | — | |
| SCHEMBL11311823 | 0.75 | CDC25A (0.46) | — | |
| SCHEMBL11316568 | 0.73 | SIGMAR1 (0.42) | SIGMAR1PARP1 | |
| SCHEMBL11769782 | 0.73 | ALDH1A1 (0.48) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL11230479 | 0.73 | SIGMAR1 (0.60) | SIGMAR1TP53 | |
| Hydrochloric Acid SCHEMBL11773268 | 0.72 | ALDH1A1 (0.47) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL11825818 | 0.71 | DRD3 (0.63) | SIGMAR1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4251538-A | Indolealkylamines and processes for their preparation | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1981-02-17 | — | — | US | disclosed |