Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CNR2 | P34972 | 5/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11319163 | 0.86 | CNR2 (0.44) | TSHRCNR2CYP2C19ALDH1A1LMNA | |
| SCHEMBL11308287 | 0.85 | TSHR (0.38) | TSHRCNR2CYP2C19ALDH1A1KDM4E | |
| SCHEMBL11323831 | 0.83 | NR3C1 (0.42) | NR3C1 | |
| SCHEMBL11315361 | 0.79 | TSHR (0.47) | TSHRCNR2CYP2C19NR1H2NR1H3 | |
| SCHEMBL1533790 | 0.78 | TSHR (0.48) | TSHRCNR2CYP2C19ALDH1A1KDM4E | |
| SCHEMBL11322183 | 0.78 | NR3C1 (0.52) | ALDH1A1KDM4EMAPTNR3C1 | |
| SCHEMBL11305990 | 0.76 | TDP1 (0.37) | ALDH1A1KDM4ELMNATDP1NR3C1 | |
| SCHEMBL9749583 | 0.76 | TSHR (0.50) | TSHRCNR2CYP2C19NR1H2NR1H3 | |
| SCHEMBL11319605 | 0.76 | TSHR (0.44) | TSHRCNR2CYP2C19NR1H2NR1H3 | |
| SCHEMBL11307225 | 0.75 | AOC3 (0.34) | TSHRLMNAAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4268439-A | Basic azo dyestuffs having benzylammoniumamine substituent in the coupling component | BAYER AKTIENGESELLSCHAFT (DE) | 1981-05-19 | — | — | US | disclosed |