Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1533790 | 0.86 | TSHR (0.48) | TSHRCYP2C19CNR2NR3C1ALDH1A1 | |
| SCHEMBL11098226 | 0.84 | FFAR1 (0.42) | TSHRCNR2ALDH1A1FFAR1GPR84 | |
| SCHEMBL9750090 | 0.79 | TSHR (0.39) | TSHRCYP2C19CNR2NR3C1ALDH1A1 | |
| SCHEMBL11160283 | 0.77 | NR3C1 (0.43) | TSHRCYP2C19NR3C1ALDH1A1PGR | |
| SCHEMBL9619470 | 0.76 | CYP2C19 (0.58) | TSHRCYP2C19CNR2NR3C1ALDH1A1 | |
| SCHEMBL11306094 | 0.76 | TSHR (0.54) | TSHRCYP2C19CNR2NR3C1ALDH1A1 | |
| SCHEMBL5406966 | 0.75 | NR3C1 (0.42) | TSHRCYP2C19NR3C1ALDH1A1PGR | |
| SCHEMBL7148219 | 0.74 | TSHR (0.54) | TSHRCYP2C19CNR2NR3C1ALDH1A1 | |
| SCHEMBL10775313 | 0.74 | CYP2C19 (0.51) | TSHRCYP2C19CNR2NR3C1NR1H2 | |
| SCHEMBL11348653 | 0.74 | TSHR (0.41) | TSHRCYP2C19NR3C1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5118986-A | Electroluminescent device | RICOH COMPANY, LTD. (JP) | 1992-06-02 | — | — | US | claimed |