Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 4/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NQO1 | P15559 | 1/20 | 0.35 |
| ▸ | POR | P16435 | 1/20 | 0.35 |
| ▸ | CYP24A1 | Q07973 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11308144 | 1.00 | MEN1 (0.43) | MEN1KMT2AALDH1A1APPMAPT | |
| SCHEMBL29044686 | 0.84 | METAP1 (0.46) | MEN1KMT2AALDH1A1MAPTCA1 | |
| SCHEMBL11292464 | 0.81 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1APPMAPT | |
| SCHEMBL11293009 | 0.81 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1APPMAPT | |
| SCHEMBL12512832 | 0.72 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1APPMAPT | |
| SCHEMBL11305757 | 0.72 | PDK2 (0.45) | MAPTCA1CA4CA7CA9 | |
| SCHEMBL11305762 | 0.72 | PDK2 (0.45) | MAPTCA1CA4CA7CA9 | |
| SCHEMBL12865658 | 0.69 | HSD17B1 (0.46) | CA1CA2CA4CA7CA9 | |
| SCHEMBL29187723 | 0.69 | PDK2 (0.49) | MEN1KMT2AALDH1A1APPMAPT | |
| SCHEMBL6355956 | 0.68 | CYP3A4 (0.38) | MEN1KMT2AALDH1A1APPMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0005821-B1 | INDANAMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1982-12-08 | — | — | EP | disclosed |
| EP-0005821-A1 | Indanamine derivatives, process for their preparation and medicaments containing them | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1979-12-12 | — | — | EP | disclosed |