Ether

Ether

SCHEMBL11308403

CCOCC.O=C(O)CCC(O)(C(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 4/20 0.44
SRC P12931 1/20 0.41
NR4A2 P43354 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
POLB P06746 2/20 0.37
CYP2C19 P33261 2/20 0.37
HIF1A Q16665 1/20 0.37
ALDH1A1 P00352 4/20 0.36
ESR1 P03372 1/20 0.36
CYP3A4 P08684 1/20 0.36
ESR2 Q92731 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
CES2 O00748 2/20 0.36
GAA P10253 1/20 0.36
HDAC3 O15379 1/20 0.36
HDAC4 P56524 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC7 Q8WUI4 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC10 Q969S8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methoxymethane SCHEMBL5530887 0.89 CES1 (0.51) CES1SRCNR4A2POLBCYP2C19
SCHEMBL11533981 0.89 NR4A2 (0.47) CES1SRCNR4A2SMN1; SMN2CYP2C19
SCHEMBL11313558 0.89 LMNA (0.43) CES1SRCNR4A2SMN1; SMN2POLB
Ether SCHEMBL11494501 0.87 SMN1; SMN2 (0.50) CES1SRCSMN1; SMN2POLBALDH1A1
Ether SCHEMBL11491206 0.87 AKT1 (0.45) CES1SRCSMN1; SMN2POLBALDH1A1
SCHEMBL11310480 0.86 CES1 (0.40) CES1ALDH1A1CES2GAALMNA
SCHEMBL11308424 0.85 CES1 (0.41) CES1SRCNR4A2POLBCYP2C19
SCHEMBL11315918 0.84 CES1 (0.43) CES1SRCNR4A2CYP2C19HIF1A
SCHEMBL11307176 0.84 PLA2G4B (0.43) CES1ALDH1A1NPSR1CES2LMNA
SCHEMBL11320202 0.84 PLA2G4B (0.43) CES1ALDH1A1NPSR1CES2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4253918-A FOR PAPER SUBSTRATES PFIZER INC. (US) 1981-03-03 US disclosed
US-4179478-A Process for the production of binders BAYER AKTIENGESELLSCHAFT (DE) 1979-12-18 US disclosed
US-4162274-A Crosslinkable urethane resins containing vinyl and carboxyl groups BAYER AKTIENGESELLSCHAFT (DE) 1979-07-24 US disclosed
US-4107012-A COATINGS, PRINTING INKS BAYER AKTIENGESELLSCHAFT (DE) 1978-08-15 US disclosed
US-4081492-A POLYEPOXIDE BINDERS BAYER AKTIENGESELLSCHAFT (DT) 1978-03-28 US disclosed
US-4049745-A REACTION PRODUCT OF POLYEPOXIDE AND AN ACRYLIC ACID BAYER AKTIENGESELLSCHAFT (DT) 1977-09-20 US disclosed
US-4014771-A POLYEPOXIDES, BINDERS FOR PRINTING INKS BAYER AKTIENGESELLSCHAFT (DT) 1977-03-29 US disclosed