Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | CES1 | P23141 | 4/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 3/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | SCN1A | P35498 | 2/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11310480 | 0.92 | CES1 (0.40) | LMNACES1CES2TSHRALDH1A1 | |
| SCHEMBL11314618 | 0.90 | PLA2G4B (0.43) | LMNACES1CES2TSHRNPSR1 | |
| SCHEMBL11320202 | 0.90 | PLA2G4B (0.43) | LMNACES1CES2TSHRNPSR1 | |
| SCHEMBL11307176 | 0.90 | PLA2G4B (0.43) | LMNACES1CES2TSHRNPSR1 | |
| Ether SCHEMBL11308403 | 0.89 | CES1 (0.44) | LMNACES1SRCCES2NR4A2 | |
| SCHEMBL11522093 | 0.88 | AKT1 (0.43) | LMNACES1SRCCES2CYP2C19 | |
| Methoxymethane SCHEMBL5530887 | 0.87 | CES1 (0.51) | LMNACES1SRCNR4A2CYP2C19 | |
| SCHEMBL11533981 | 0.87 | NR4A2 (0.47) | LMNACES1SRCNR4A2CYP2C19 | |
| SCHEMBL11308358 | 0.83 | LMNA (0.40) | LMNACES1SRCCYP2C19CYP3A4 | |
| SCHEMBL11308424 | 0.82 | CES1 (0.41) | CES1SRCNR4A2CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4253918-A | FOR PAPER SUBSTRATES | PFIZER INC. (US) | 1981-03-03 | — | — | US | disclosed |
| US-4179478-A | Process for the production of binders | BAYER AKTIENGESELLSCHAFT (DE) | 1979-12-18 | — | — | US | disclosed |
| US-4162274-A | Crosslinkable urethane resins containing vinyl and carboxyl groups | BAYER AKTIENGESELLSCHAFT (DE) | 1979-07-24 | — | — | US | disclosed |
| US-4081492-A | POLYEPOXIDE BINDERS | BAYER AKTIENGESELLSCHAFT (DT) | 1978-03-28 | — | — | US | disclosed |
| US-4049745-A | REACTION PRODUCT OF POLYEPOXIDE AND AN ACRYLIC ACID | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-20 | — | — | US | disclosed |
| US-4014771-A | POLYEPOXIDES, BINDERS FOR PRINTING INKS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-03-29 | — | — | US | disclosed |