SCHEMBL11308477

SCHEMBL11308477

CC1(c2cccc(Br)c2)CCc2cc(Br)ccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.36
CHRNA1 P02708 1/20 0.36
CHRNG P07510 1/20 0.36
CHRNB1 P11230 1/20 0.36
CHRNB2 P17787 1/20 0.36
SLC6A2 P23975 1/20 0.36
CHRNB4 P30926 1/20 0.36
SLC6A4 P31645 1/20 0.36
CHRNA3 P32297 1/20 0.36
CHRNA4 P43681 1/20 0.36
SLC6A3 Q01959 1/20 0.36
CHRND Q07001 1/20 0.36
HCAR3 P49019 1/20 0.36
HCAR2 Q8TDS4 1/20 0.36
HSD11B1 P28845 1/20 0.36
BACE1 P56817 5/20 0.35
CTSD P07339 1/20 0.35
CYP2C19 P33261 1/20 0.35
PARP1 P09874 1/20 0.34
PNMT P11086 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2223847 0.74 KDM1A (0.43) KDM1ABACE1PARP1PNMTAPP
SCHEMBL28617264 0.72 KDM1A (0.42) KDM1A
SCHEMBL18085630 0.71 KDM1A (0.41) KDM1ABACE1PARP1PNMTAPP
SCHEMBL30721221 0.71 KDM1A (0.41) KDM1ABACE1PARP1PNMTAPP
SCHEMBL2016698 0.71 BACE1 (0.43) KDM1ABACE1PARP1PNMTAPP
SCHEMBL12501599 0.71 KDM1A (0.45) KDM1ASLC6A2SLC6A3BACE1CYP2C19
SCHEMBL28884828 0.71 KDM1A (0.41) KDM1ABACE1PARP1PNMTAPP
Hydrochloric Acid SCHEMBL30016185 0.70 KDM1A (0.44) KDM1ASLC6A2SLC6A3BACE1CYP2C19
SCHEMBL9918032 0.70 OPRD1 (0.44) KDM1ACHRNA1CHRNGCHRNB1CHRNB2
SCHEMBL21427237 0.70 GABRA1 (0.39) HCAR3HCAR2PNMTSRD5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4255285-A FOR THE CATALYTIC OXIDATION OF A 1-PHENYLINDAN TO AN ANTHRAQUINONE; ATOMIZING AN AQUEOUS VANADIUM COMPOUND TO COAT AND ROAST MOVING CARRIER PARTICLES BASF AKTIENGESELLSCHAFT (DE) 1981-03-10 US disclosed