Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRHR | P34981 | 4/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11203821 | 0.94 | TRHR (0.46) | TRHR | |
| SCHEMBL11308630 | 0.94 | ACE (0.45) | TRHRACEMC4RTSHR | |
| SCHEMBL29592647 | 0.92 | MC4R (0.41) | TRHRMC4R | |
| SCHEMBL11203817 | 0.89 | TRHR (0.46) | TRHR | |
| SCHEMBL4956842 | 0.89 | TRHR (0.46) | TRHR | |
| SCHEMBL11798918 | 0.89 | CTSL (0.39) | TRHRMC4R | |
| SCHEMBL29630670 | 0.89 | TRHR (0.42) | TRHRACETSHR | |
| SCHEMBL11796296 | 0.89 | TRHR (0.39) | TRHR | |
| SCHEMBL29958712 | 0.88 | TRHR (0.41) | TRHRACE | |
| SCHEMBL11792360 | 0.88 | CTSL (0.38) | TRHRMC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-56059714-A | — | — | None | — | — | JP | disclosed |
| JP-S5659714-A | IMPROVER AND REMEDY FOR DYSBULIA OR DEPRESSION | TANABE SEIYAKU CO LTD | 1981-05-23 | — | — | JP | disclosed |