Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 2/20 | 0.58 |
| ▸ | AKT1 | P31749 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | INSR | P06213 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30786725 | 0.84 | ALDH1A1 (0.52) | ALDH1A1KDM4EGAATSHRRAB9A | |
| SCHEMBL11110793 | 0.84 | ALDH1A1 (0.52) | ALDH1A1KDM4EGAATSHRRAB9A | |
| SCHEMBL30786724 | 0.84 | ALDH1A1 (0.52) | ALDH1A1KDM4EGAATSHRRAB9A | |
| SCHEMBL4842042 | 0.83 | CYP3A4 (0.47) | CFDAKT1CYP3A4ALDH1A1KDM4E | |
| SCHEMBL1901977 | 0.81 | ALDH1A1 (0.45) | CFDAKT1ALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL3987965 | 0.81 | CFD (0.46) | CFDAKT1CYP3A4ALDH1A1PTGS1 | |
| SCHEMBL10908806 | 0.79 | ALDH1A1 (0.50) | CYP3A4ALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL178979 | 0.79 | CFD (0.69) | CFDAKT1ALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL11107426 | 0.79 | ALDH1A1 (0.43) | CFDAKT1ALDH1A1ALOX5KDM4E | |
| SCHEMBL11324429 | 0.78 | ALDH1A1 (0.39) | CFDAKT1CYP3A4ALDH1A1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4248976-A | COMPRISING A PHOSPHORUS COMPOUND AND AN AROMATIC COMPOUND | CIBA-GEIGY AG (CH) | 1981-02-03 | — | — | US | disclosed |