Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | G6PD | P11413 | 1/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11306224 | 0.85 | HDAC1 (0.62) | LMNAKMT2AMEN1HDAC1HDAC8 | |
| SCHEMBL11689166 | 0.85 | HDAC1 (0.59) | KMT2AMEN1HDAC1HDAC8HDAC6 | |
| SCHEMBL11306555 | 0.84 | MAPK1 (0.65) | KMT2AMEN1NPC1CYP3A4RAB9A | |
| SCHEMBL11692577 | 0.82 | HDAC1 (0.57) | LMNAKMT2AMEN1HDAC1HDAC8 | |
| SCHEMBL11692881 | 0.81 | MAPT (0.48) | LMNAKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL16592539 | 0.78 | KCNMA1 (0.77) | RORCLMNACRHBPCRHR2KMT2A | |
| SCHEMBL29886218 | 0.78 | KCNMA1 (0.77) | RORCLMNACRHBPCRHR2KMT2A | |
| SCHEMBL11307445 | 0.77 | KDM4E (0.60) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL11320747 | 0.75 | ALDH1A1 (0.64) | LMNAKMT2AMEN1NPC1RAB9A | |
| SCHEMBL11313551 | 0.75 | KDM4E (0.62) | KMT2AMEN1HDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4263205-A | FOR COLORING POLYMERS, LACQUERS | CIBA-GEIGY CORPORATION (US) | 1981-04-21 | — | — | US | disclosed |
| EP-0006154-A1 | Monoazo pigments and their use in colouring high molecular-weight organic material | CIBA-GEIGY AG (CH) | 1980-01-09 | — | — | EP | disclosed |
| US-4062838-A | LACQUERS, PRINTING INKS, YELLOW TO ORANGE | CIBA-GEIGY CORPORATION (US) | 1977-12-13 | — | — | US | disclosed |