Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | NQO1 | P15559 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7329813 | 0.73 | NQO1 (0.67) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11320953 | 0.73 | MEN1 (0.44) | DHFRKDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL23544689 | 0.72 | NQO1 (0.54) | DHFRKDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL26838103 | 0.72 | NQO1 (0.54) | SMN1; SMN2KMT2AMEN1ACACBNQO1 | |
| SCHEMBL11317840 | 0.72 | ALDH1A1 (0.49) | DHFRKDM4EALDH1A1SMN1; SMN2NQO1 | |
| SCHEMBL11317835 | 0.71 | NQO1 (0.39) | DHFRKDM4EALDH1A1SMN1; SMN2KMT2A | |
| Ethylene SCHEMBL27922059 | 0.70 | NQO1 (0.61) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL27056972 | 0.69 | TSHR (0.44) | KMT2AMEN1ACACBTP53MAPT | |
| SCHEMBL11681710 | 0.69 | ATM (0.45) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL11317842 | 0.69 | DHFR (0.45) | DHFRKDM4EALDH1A1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4268439-A | Basic azo dyestuffs having benzylammoniumamine substituent in the coupling component | BAYER AKTIENGESELLSCHAFT (DE) | 1981-05-19 | — | — | US | disclosed |