Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25694634 | 1.00 | TSHR (0.56) | TSHRALDH1A1L3MBTL1LMNASLC1A1 | |
| SCHEMBL8586587 | 0.93 | ALDH1A1 (0.56) | TSHRALDH1A1L3MBTL1LMNAPPARG | |
| SCHEMBL28444110 | 0.93 | ALDH1A1 (0.56) | TSHRALDH1A1L3MBTL1LMNAPPARG | |
| SCHEMBL8584594 | 0.93 | ALDH1A1 (0.56) | TSHRALDH1A1L3MBTL1LMNAPPARG | |
| SCHEMBL5306511 | 0.93 | ALDH1A1 (0.56) | TSHRALDH1A1L3MBTL1LMNAPPARG | |
| Hydrochloric Acid SCHEMBL8144696 | 0.91 | ALDH1A1 (0.54) | TSHRALDH1A1L3MBTL1LMNAPPARG | |
| Hydrochloric Acid SCHEMBL26626701 | 0.91 | ALDH1A1 (0.54) | TSHRALDH1A1L3MBTL1LMNAPPARG | |
| SCHEMBL10929865 | 0.90 | TSHR (0.50) | TSHRALDH1A1L3MBTL1LMNASLC1A1 | |
| SCHEMBL19416404 | 0.88 | TSHR (0.52) | TSHRALDH1A1L3MBTL1LMNASLC1A1 | |
| SCHEMBL20064043 | 0.88 | TSHR (0.52) | TSHRALDH1A1L3MBTL1LMNASLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4275192-A | ANTINEOPLASTIC AND ANTIVIRAL ACTIVITY | G. D. SEARLE & CO. (US) | 1981-06-23 | — | — | US | disclosed |