Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1233135 | 0.98 | L3MBTL1 (0.51) | TSHRL3MBTL1ALDH1A1LMNASLC1A1 | |
| SCHEMBL25694634 | 0.88 | TSHR (0.56) | TSHRL3MBTL1ALDH1A1LMNASLC1A1 | |
| SCHEMBL11310489 | 0.88 | TSHR (0.56) | TSHRL3MBTL1ALDH1A1LMNASLC1A1 | |
| SCHEMBL2948709 | 0.86 | TSHR (0.50) | TSHRL3MBTL1ALDH1A1LMNASLC1A1 | |
| SCHEMBL8586587 | 0.85 | ALDH1A1 (0.56) | TSHRL3MBTL1ALDH1A1LMNAPPARG | |
| SCHEMBL5306511 | 0.85 | ALDH1A1 (0.56) | TSHRL3MBTL1ALDH1A1LMNAPPARG | |
| SCHEMBL8584594 | 0.85 | ALDH1A1 (0.56) | TSHRL3MBTL1ALDH1A1LMNAPPARG | |
| SCHEMBL28444110 | 0.85 | ALDH1A1 (0.56) | TSHRL3MBTL1ALDH1A1LMNAPPARG | |
| SCHEMBL19416404 | 0.85 | TSHR (0.52) | TSHRL3MBTL1ALDH1A1LMNASLC1A1 | |
| Hydrochloric Acid SCHEMBL4740477 | 0.84 | SLC1A1 (0.49) | TSHRL3MBTL1ALDH1A1LMNASLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018069863-A1 | 1,3 DI-SUBSTITUTED CYCLOBUTANE OR AZETIDINE DERIVATIVES AS HEMATOPOIETIC PROSTAGLANDIN D SYNTHASE INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-04-19 | — | — | WO | disclosed |