Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.56 |
| ▸ | RECQL | P46063 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TEK | Q02763 | 1/20 | 0.56 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 1/20 | 0.49 |
| ▸ | RARG | P13631 | 1/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.49 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11311253 | 1.00 | KDM4E (0.56) | KDM4ERECQLTDP1HPGDPOLB | |
| SCHEMBL11313189 | 0.94 | KDM4E (0.60) | KDM4ERECQLTDP1HPGDPOLB | |
| SCHEMBL11313191 | 0.94 | KDM4E (0.60) | KDM4ERECQLTDP1HPGDPOLB | |
| Carbenicillin Phenyl SCHEMBL11310852 | 0.87 | LMNA (0.64) | KDM4ERECQLTDP1HPGDPOLB | |
| Carbenicillin Phenyl SCHEMBL11310839 | 0.87 | LMNA (0.64) | KDM4ERECQLTDP1HPGDPOLB | |
| SCHEMBL11309237 | 0.87 | KDM4E (0.57) | KDM4ERECQLTDP1HPGDPOLB | |
| SCHEMBL11309239 | 0.87 | KDM4E (0.57) | KDM4ERECQLTDP1HPGDPOLB | |
| SCHEMBL10735137 | 0.86 | KDM4E (0.64) | KDM4ERECQLTDP1HPGDPOLB | |
| SCHEMBL10735144 | 0.86 | KDM4E (0.64) | KDM4ERECQLTDP1HPGDPOLB | |
| SCHEMBL11311245 | 0.82 | CYP2C19 (0.54) | KDM4ERECQLTDP1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4304717-A | Process for the preparation of reactive penicillanic acid and cephalosporanic acid derivatives | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT (HU) | 1981-12-08 | — | — | US | disclosed |
| US-4171303-A | Process for the preparation of reactive penicillanic acid and cephalosporanic acid derivatives | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1979-10-16 | — | — | US | disclosed |