Fluoride

Fluoride

SCHEMBL1131141

C1=CC(CCCc2ccccc2)=C([Hf]C2=C(CCCc3ccccc3)C=CC2)C1.F.F

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.39
SIGMAR1 Q99720 5/20 0.37
MAOA P21397 1/20 0.36
HTR3A P46098 1/20 0.36
POLB P06746 1/20 0.36
MAOB P27338 2/20 0.35
IDO1 P14902 1/20 0.34
HDAC3 O15379 1/20 0.34
MAPK1 P28482 1/20 0.34
ADRA1A P35348 1/20 0.34
HDAC4 P56524 1/20 0.34
SLC6A3 Q01959 1/20 0.34
HDAC1 Q13547 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HDAC7 Q8WUI4 1/20 0.34
HDAC2 Q92769 1/20 0.34
HDAC10 Q969S8 1/20 0.34
HDAC11 Q96DB2 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL27619066 0.78 HTR2A (0.40) HTR2ASIGMAR1MAOAPOLBMAOB
Fluoride SCHEMBL27619052 0.78 HTR2A (0.40) HTR2ASIGMAR1MAOAPOLBMAOB
SCHEMBL4576937 0.77 CALM1 (0.39) MAOAMAOBADRA1ASMN1; SMN2
Fluoride SCHEMBL1131527 0.77 HTR2A (0.39) HTR2ASIGMAR1MAOAPOLBMAOB
Fluoride SCHEMBL1130344 0.75
Fluoride Ion SCHEMBL27619051 0.75 HTR2A (0.40) HTR2ASIGMAR1MAOAMAOBIDO1
Fluoride Ion SCHEMBL27619063 0.75 HTR2A (0.40) HTR2ASIGMAR1MAOAMAOBIDO1
Hydrochloric Acid SCHEMBL7552325 0.72 SIGMAR1 (0.39) HTR2ASIGMAR1MAOBADRA1ASLC6A3
Hydrochloric Acid SCHEMBL3353879 0.72
Hydrochloric Acid SCHEMBL7548183 0.71 HTR2A (0.37) HTR2ASIGMAR1MAOAMAOBIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1673401-B1 POLYMERIZATION PROCESS AND CONTROL OF POLYMER COMPOSITION PROPERTIES UNIVATION TECH LLC (US) 2015-10-21 EP disclosed
EP-1546212-B1 BIMODAL POLYOLEFIN PRODUCTION PROCESS AND FILMS THEREFROM UNIVATION TECH LLC (US) 2011-02-16 EP disclosed
EP-1673400-A4 POLYMERIZATION PROCESS AND CONTROL OF POLYMER COMPOSITION PROPERTIES UNIVATION TECH LLC (US) 2007-07-11 EP disclosed
EP-1673401-A4 POLYMERIZATION PROCESS AND CONTROL OF POLYMER COMPOSITION PROPERTIES UNIVATION TECH LLC (US) 2007-07-11 EP disclosed
US-7238756-B2 Polymerization process and control of polymer composition properties UNIVATION TECHNOLOGIES, LLC (US) 2007-07-03 US disclosed
EP-1551553-A4 PROCESS FOR PRODUCING FLUORINATED CATALYSTS UNIVATION TECH LLC (US) 2007-05-09 EP disclosed
EP-1546212-A4 BIMODAL POLYOLEFIN PRODUCTION PROCESS AND FILMS THEREFROM UNIVATION TECH LLC (US) 2006-07-05 EP disclosed
EP-1673401-A1 POLYMERIZATION PROCESS AND CONTROL OF POLYMER COMPOSITION PROPERTIES Univation Technologies, LLC (US) 2006-06-28 EP disclosed
EP-1673400-A1 POLYMERIZATION PROCESS AND CONTROL OF POLYMER COMPOSITION PROPERTIES Univation Technologies, LLC (US) 2006-06-28 EP disclosed
EP-1560857-A4 SYNTHESIS OF POLYMERIZATION CATALYST COMPONENTS UNIVATION TECH LLC (US) 2006-04-19 EP disclosed
US-20050038210-A1 Bimodal polyolefin production process and films therefrom KUO CHI-I (US) 2005-02-17 US disclosed
US-6855784-B2 Synthesis of polymerization catalyst components UNIVATION TECHNOLOGIES, LLC (US) 2005-02-15 US disclosed
US-6828395-B1 Polymerization process and control of polymer composition properties UNIVATION TECHNOLOGIES, LLC 2004-12-07 US disclosed
US-20040236045-A1 SYNTHESIS OF POLYMERIZATION CATALYST COMPONENTS MATSUNAGA PHILLIP T (US) 2004-11-25 US disclosed
WO-2004044010-A2 SYNTHESIS OF POLYMERIZATION CATALYST COMPONENTS UNIVATION TECHNOLOGIES, LLC (US) 2004-05-27 WO disclosed
US-20040092387-A1 Synthesis of polymerization catalyst components UNIVATION TECHNOLOGIES, LLC 2004-05-13 US disclosed
WO-2004022230-A1 PROCESS FOR PRODUCING FLUORINATED CATALYSTS UNIVATION TECHNOLOGIES, LLC (US) 2004-03-18 WO disclosed
WO-2004022607-A1 BIMODAL POLYOLEFIN PRODUCTION PROCESS AND FILMS THEREFROM UNIVATION TECHNOLOGIES, LLC (US) 2004-03-18 WO disclosed
US-20040043893-A1 Process for producing fluorinated catalysts UNIVATION TECHNOLOGIES, LLC 2004-03-04 US disclosed
US-20040044154-A1 Bimodal polyolefin production process and films therefrom UNIVATION TECHNOLOGIES, LLC 2004-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040043893-A1 Process for producing fluorinated catalysts FLI1, AFF1, INF2 HTR2A 3132/4885SIGMAR1 1013/4885MAOA 3240/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.