Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.40 |
| ▸ | EDNRA | P25101 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7552511 | 0.87 | KDM1A (0.42) | TP53L3MBTL1MTNR1AMTNR1BMEN1 | |
| SCHEMBL11316242 | 0.83 | TP53 (0.41) | TP53L3MBTL1MTNR1AMTNR1BMEN1 | |
| SCHEMBL11311499 | 0.81 | CYP1A2 (0.45) | MTNR1AMTNR1BMEN1CYP1A2CYP3A4 | |
| SCHEMBL11523163 | 0.80 | FFAR1 (0.43) | TP53L3MBTL1FFAR1EGFR | |
| SCHEMBL21978182 | 0.77 | TP53 (0.41) | TP53L3MBTL1FFAR1EGFR | |
| SCHEMBL31326550 | 0.77 | TP53 (0.41) | TP53L3MBTL1FFAR1EGFR | |
| SCHEMBL11015326 | 0.77 | SLC6A2 (0.42) | TP53L3MBTL1FFAR1EGFR | |
| SCHEMBL11308894 | 0.77 | SIGMAR1 (0.41) | MTNR1AMTNR1BMEN1CYP1A2CYP3A4 | |
| SCHEMBL13051100 | 0.77 | SIGMAR1 (0.47) | MEN1KMT2ASIGMAR1HTR2AHTR2C | |
| SCHEMBL13050842 | 0.75 | OPRM1 (0.47) | MTNR1AMTNR1BMEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4246281-A | ANTIINFLAMMATORY AGENTS | LILLY INDUSTRIES LIMITED (GB) | 1981-01-20 | — | — | US | disclosed |