Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | GSK3B | P49841 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | F3 | P13726 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11311651 | 1.00 | LMNA (0.58) | LMNATDP1GSK3BSMN1; SMN2F3 | |
| SCHEMBL20358071 | 0.91 | LMNA (0.63) | LMNATDP1GSK3BSMN1; SMN2F3 | |
| SCHEMBL11311432 | 0.86 | CA12 (0.51) | LMNASMN1; SMN2KMT2AMAPTGAA | |
| SCHEMBL11312847 | 0.83 | LMNA (0.50) | LMNAATMMEN1KMT2AMAPT | |
| SCHEMBL6276084 | 0.83 | LMNA (0.60) | LMNATDP1GSK3BSMN1; SMN2F3 | |
| SCHEMBL11312851 | 0.83 | LMNA (0.50) | LMNAATMMEN1KMT2AMAPT | |
| SCHEMBL13699435 | 0.83 | LMNA (0.54) | LMNATDP1GSK3BSMN1; SMN2F3 | |
| SCHEMBL11309624 | 0.82 | LMNA (0.58) | LMNASMN1; SMN2F3MEN1KMT2A | |
| SCHEMBL11309627 | 0.82 | LMNA (0.58) | LMNASMN1; SMN2F3MEN1KMT2A | |
| SCHEMBL10428067 | 0.81 | LMNA (0.69) | LMNATDP1GSK3BSMN1; SMN2F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4259350-A | PROTECTING DEGRADABLE ORGANIC MATERIAL FROM FUNGAL OR INSECT ATTACK | SANKYO COMPANY LIMITED (JP) | 1981-03-31 | — | — | US | disclosed |