Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | F3 | P13726 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20358071 | 0.88 | LMNA (0.63) | LMNATDP1GSK3BSMN1; SMN2F3 | |
| SCHEMBL11311651 | 0.83 | LMNA (0.58) | LMNATDP1GSK3BSMN1; SMN2F3 | |
| SCHEMBL11311620 | 0.83 | LMNA (0.58) | LMNATDP1GSK3BSMN1; SMN2F3 | |
| SCHEMBL12870316 | 0.82 | GSK3B (0.61) | TDP1GSK3BSMN1; SMN2F3MEN1 | |
| SCHEMBL6276084 | 0.80 | LMNA (0.60) | LMNATDP1GSK3BSMN1; SMN2F3 | |
| SCHEMBL9855983 | 0.77 | LMNA (0.68) | LMNATDP1GSK3BSMN1; SMN2F3 | |
| SCHEMBL9855976 | 0.77 | LMNA (0.68) | LMNATDP1GSK3BSMN1; SMN2F3 | |
| 4-Methoxy Ethyl Cinnamate SCHEMBL15190 | 0.76 | CA12 (0.71) | LMNATDP1GSK3BSMN1; SMN2F3 | |
| 4-Methoxy Ethyl Cinnamate SCHEMBL1056347 | 0.76 | CA12 (0.71) | LMNATDP1GSK3BSMN1; SMN2F3 | |
| 4-Methoxy Ethyl Cinnamate SCHEMBL434842 | 0.76 | CA12 (0.71) | LMNATDP1GSK3BSMN1; SMN2F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090232753-A1 | Gel compositions | HEALY LIN LU | 2009-09-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090232753-A1 | Gel compositions | PGR, COPE, PTGER1 | LMNA 1427/4885TDP1 3637/4885GSK3B 1681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.