Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.75 |
| ▸ | GNG2 | P59768 | 5/20 | 0.72 |
| ▸ | GNB1 | P62873 | 5/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | CCR6 | P51684 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.62 |
| ▸ | P2RY4 | P51582 | 7/20 | 0.61 |
| ▸ | P2RY2 | P41231 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11340829 | 0.99 | PHLPP2 (0.77) | PHLPP2GNG2GNB1CYP1A2CYP2C9 | |
| SCHEMBL11311709 | 0.88 | MEN1 (0.80) | MEN1POLBCCR6BLMKMT2A | |
| SCHEMBL3016037 | 0.88 | P2RY4 (0.78) | PHLPP2GNG2GNB1CYP1A2CYP2C9 | |
| SCHEMBL790823 | 0.88 | GNG2 (0.83) | PHLPP2GNG2GNB1CYP1A2CYP2C9 | |
| SCHEMBL13021512 | 0.88 | GNG2 (0.92) | PHLPP2GNG2GNB1CYP1A2CYP2C9 | |
| SCHEMBL2854079 | 0.87 | PHLPP2 (0.98) | PHLPP2GNG2GNB1CYP1A2CYP2C9 | |
| SCHEMBL13214019 | 0.87 | P2RY4 (0.80) | PHLPP2GNG2GNB1CYP1A2CYP2C9 | |
| SCHEMBL13213975 | 0.86 | GNG2 (0.86) | PHLPP2GNG2GNB1CYP1A2CYP2C9 | |
| SCHEMBL791019 | 0.86 | GNG2 (0.85) | PHLPP2GNG2GNB1CYP1A2CYP2C9 | |
| SCHEMBL29357302 | 0.86 | GNG2 (0.85) | PHLPP2GNG2GNB1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4289496-A | LOW LIQUID TO MATERIAL RATIO RESULTING IN UNIFORMITY OF FINISHING | SANDOZ LTD. (CH) | 1981-09-15 | — | — | US | disclosed |
| US-4260389-A | FINISHING AGENT, WATER, FOAMING AGENT; DYEING | SANDOZ LTD. (CH) | 1981-04-07 | — | — | US | disclosed |