Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY4 known ✓ | P51582 | 11/20 | 0.79 |
| ▸ | P2RY2 known ✓ | P41231 | 8/20 | 0.77 |
| ▸ | P2RY12 known ✓ | Q9H244 | 8/20 | 0.76 |
| ▸ | P2RY6 known ✓ | Q15077 | 4/20 | 0.76 |
| ▸ | P2RY1 known ✓ | P47900 | 2/20 | 0.76 |
| ▸ | MEN1 | O00255 | 1/20 | 0.80 |
| ▸ | POLB | P06746 | 1/20 | 0.80 |
| ▸ | CCR6 | P51684 | 1/20 | 0.80 |
| ▸ | BLM | P54132 | 1/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.80 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.80 |
| ▸ | CDK2 | P24941 | 2/20 | 0.76 |
| ▸ | ENTPD1 | P49961 | 2/20 | 0.73 |
| ▸ | MET | P08581 | 2/20 | 0.72 |
| ▸ | HGF | P14210 | 2/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11340829 | 0.89 | PHLPP2 (0.77) | MEN1POLBCCR6BLMKMT2A | |
| SCHEMBL11311715 | 0.88 | PHLPP2 (0.75) | MEN1POLBCCR6BLMKMT2A | |
| SCHEMBL3016033 | 0.88 | P2RY4 (1.00) | P2RY4P2RY2P2RY12P2RY6CDK2 | |
| SCHEMBL29356677 | 0.87 | P2RY2 (1.00) | P2RY4P2RY2P2RY12P2RY6CDK2 | |
| Acid Blue 25 SCHEMBL29355038 | 0.87 | P2RY4 (1.00) | P2RY4P2RY2P2RY12P2RY6CDK2 | |
| Acid Blue 25 SCHEMBL790822 | 0.87 | P2RY4 (1.00) | P2RY4P2RY2P2RY12P2RY6CDK2 | |
| SCHEMBL3021097 | 0.85 | P2RY4 (1.00) | P2RY4P2RY2P2RY12P2RY6CDK2 | |
| SCHEMBL31616829 | 0.84 | P2RY2 (0.76) | P2RY4P2RY2P2RY12P2RY6CDK2 | |
| SCHEMBL31616828 | 0.84 | P2RY2 (0.76) | P2RY4P2RY2P2RY12P2RY6CDK2 | |
| SCHEMBL3029895 | 0.84 | MET (0.93) | P2RY4P2RY2P2RY12P2RY6CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4289496-A | LOW LIQUID TO MATERIAL RATIO RESULTING IN UNIFORMITY OF FINISHING | SANDOZ LTD. (CH) | 1981-09-15 | — | — | US | disclosed |
| US-4260389-A | FINISHING AGENT, WATER, FOAMING AGENT; DYEING | SANDOZ LTD. (CH) | 1981-04-07 | — | — | US | disclosed |