Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.58 |
| ▸ | HRH1 | P35367 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11305599 | 0.89 | L3MBTL1 (0.60) | L3MBTL1POLBMAPK1LMNANPC1 | |
| SCHEMBL11439814 | 0.87 | NPC1 (0.65) | L3MBTL1POLBMAPK1LMNANPC1 | |
| SCHEMBL11320117 | 0.84 | L3MBTL1 (0.53) | L3MBTL1POLBMAPK1LMNANPC1 | |
| SCHEMBL11485976 | 0.83 | L3MBTL1 (0.62) | HRH2HRH1L3MBTL1TDP1POLB | |
| SCHEMBL11425838 | 0.83 | L3MBTL1 (0.56) | L3MBTL1TDP1POLBNPC1MAPT | |
| SCHEMBL11308352 | 0.83 | NPC1 (0.62) | L3MBTL1MAPK1LMNANPC1MAPT | |
| SCHEMBL21567532 | 0.82 | HRH2 (0.61) | HRH2HRH1L3MBTL1TDP1MAPK1 | |
| SCHEMBL9753438 | 0.82 | L3MBTL1 (0.65) | HRH2HRH1L3MBTL1TDP1MAPK1 | |
| SCHEMBL11886540 | 0.80 | NPC1 (0.65) | L3MBTL1POLBMAPK1NPC1MAPT | |
| SCHEMBL11306590 | 0.80 | L3MBTL1 (0.52) | L3MBTL1TDP1POLBMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0004334-B1 | CARBAMATES AND THEIR PESTICIDAL COMPOSITIONS, PREPARATIONS THEREOF AND USE THEREOF AS PESTICIDES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-10-21 | — | — | EP | claimed |
| US-4215139-A | PESTICIDES, INSECTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1980-07-29 | — | — | US | disclosed |