Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | ESR1 | P03372 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856035 | 0.93 | L3MBTL1 (0.59) | L3MBTL1MAPTNPC1MAPK1USP2 | |
| SCHEMBL11439814 | 0.90 | NPC1 (0.65) | L3MBTL1MAPTNPC1MAPK1USP2 | |
| SCHEMBL11305599 | 0.89 | L3MBTL1 (0.60) | L3MBTL1MAPTNPC1MAPK1USP2 | |
| SCHEMBL11308352 | 0.88 | NPC1 (0.62) | L3MBTL1MAPTNPC1MAPK1USP2 | |
| SCHEMBL11312928 | 0.84 | HRH2 (0.58) | L3MBTL1MAPTNPC1MAPK1USP2 | |
| SCHEMBL11886540 | 0.83 | NPC1 (0.65) | L3MBTL1MAPTNPC1MAPK1HSD17B10 | |
| SCHEMBL11306590 | 0.82 | L3MBTL1 (0.52) | L3MBTL1MAPTNPC1MAPK1USP2 | |
| SCHEMBL11313542 | 0.80 | NPC1 (0.55) | L3MBTL1MAPTNPC1MAPK1USP2 | |
| SCHEMBL9856606 | 0.80 | L3MBTL1 (0.54) | L3MBTL1MAPTNPC1MAPK1USP2 | |
| SCHEMBL8603693 | 0.80 | MTNR1A (0.66) | L3MBTL1MAPTNPC1SMN1; SMN2MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0004334-B1 | CARBAMATES AND THEIR PESTICIDAL COMPOSITIONS, PREPARATIONS THEREOF AND USE THEREOF AS PESTICIDES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-10-21 | — | — | EP | claimed |
| US-4215139-A | PESTICIDES, INSECTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1980-07-29 | — | — | US | disclosed |