Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.67 |
| ▸ | RAB9A | P51151 | 5/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11693798 | 0.89 | NPC1 (0.60) | NPC1RAB9AL3MBTL1POLBTSHR | |
| SCHEMBL11313646 | 0.81 | POLB (0.72) | NPC1RAB9AL3MBTL1POLBALDH1A1 | |
| SCHEMBL11309805 | 0.81 | NPC1 (0.72) | NPC1RAB9AL3MBTL1POLBLMNA | |
| SCHEMBL30463822 | 0.80 | NPC1 (0.78) | NPC1RAB9AL3MBTL1POLBMEN1 | |
| SCHEMBL11315790 | 0.79 | KMT2A (0.63) | NPC1RAB9AL3MBTL1POLBALDH1A1 | |
| SCHEMBL29353454 | 0.77 | NPC1 (0.61) | NPC1RAB9AL3MBTL1POLBTSHR | |
| SCHEMBL8689566 | 0.76 | TRPM4 (0.75) | NPC1RAB9AL3MBTL1POLBALDH1A1 | |
| SCHEMBL11307891 | 0.76 | LMNA (0.58) | NPC1RAB9AL3MBTL1POLBTSHR | |
| SCHEMBL11309015 | 0.76 | POLB (0.60) | NPC1RAB9AL3MBTL1POLBTSHR | |
| SCHEMBL9400403 | 0.75 | NPC1 (0.61) | NPC1RAB9AL3MBTL1POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4263205-A | FOR COLORING POLYMERS, LACQUERS | CIBA-GEIGY CORPORATION (US) | 1981-04-21 | — | — | US | disclosed |
| US-4062838-A | LACQUERS, PRINTING INKS, YELLOW TO ORANGE | CIBA-GEIGY CORPORATION (US) | 1977-12-13 | — | — | US | disclosed |