Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4358581 | 0.81 | KMT2A (0.50) | NPC1RAB9APOLBMAPTALDH1A1 | |
| SCHEMBL6944416 | 0.77 | ALDH1A1 (0.47) | NPC1RAB9AMAPTALDH1A1MAPK1 | |
| SCHEMBL12106916 | 0.77 | TSHR (0.46) | NPC1RAB9APOLBMAPTTSHR | |
| SCHEMBL6566816 | 0.76 | POLB (0.69) | NPC1RAB9AL3MBTL1POLBMAPT | |
| SCHEMBL4626931 | 0.76 | KCNMA1 (0.52) | NPC1RAB9APOLBMAPT | |
| SCHEMBL4354187 | 0.76 | MEN1 (0.59) | NPC1RAB9AMAPTMAPK1 | |
| SCHEMBL11313664 | 0.75 | NPC1 (0.67) | NPC1RAB9AL3MBTL1POLBTSHR | |
| SCHEMBL4359810 | 0.75 | MEN1 (0.56) | NPC1RAB9APOLBMAPTTSHR | |
| SCHEMBL6944637 | 0.74 | ALDH1A1 (0.52) | RAB9AL3MBTL1POLBMAPTALDH1A1 | |
| SCHEMBL9179594 | 0.74 | POLB (0.52) | NPC1POLBTSHRALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5372917-A | Excellent color forming property, storage stability and recorded image preservability; pyrazolone derivatives | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1994-12-13 | — | — | US | disclosed |