Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.48 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.48 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.48 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11432002 | 0.86 | HIF1A (0.55) | LMNAMAPTMRGPRX4ALDH1A1SMN1; SMN2 | |
| SCHEMBL11437965 | 0.85 | HIF1A (0.56) | LMNAMAPTMRGPRX4ABCC8ALDH1A1 | |
| SCHEMBL3125880 | 0.78 | PRKDC (0.58) | LMNAMAPTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7166496 | 0.77 | PRKDC (0.56) | LMNAMAPTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10995462 | 0.77 | PRKDC (0.56) | LMNAMAPTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10693658 | 0.76 | ALDH1A1 (0.56) | LMNAMAPTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9416209 | 0.74 | SMN1; SMN2 (0.68) | LMNAMAPTALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL4602768 | 0.74 | PTPN11 (0.50) | LMNAMAPTMRGPRX4MAPK1ADRA1A | |
| SCHEMBL9312548 | 0.72 | ALDH1A1 (0.64) | LMNAMAPTMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9416202 | 0.72 | ALDH1A1 (0.73) | LMNAMAPTMAPK1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4269978-A | CHROMOGENS; ENCAPSULATED FOR REPRODUCTION AND RECORDING PURPOSES | CIBA-GEIGY CORPORATION (US) | 1981-05-26 | — | — | US | disclosed |
| US-4100169-A | USEFUL AS COLOR FORMERS | CIBA-GEIGY CORPORATION (US) | 1978-07-11 | — | — | US | disclosed |