SCHEMBL3125880

SCHEMBL3125880

O=C(O)c1ccccc1C(=O)c1ccc(N2CCCC2)cc1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 3/20 0.58
PIK3CD O00329 1/20 0.58
PIK3CA P42336 1/20 0.58
PIK3CB P42338 1/20 0.58
PIK3CG P48736 1/20 0.58
ALDH1A1 P00352 8/20 0.57
KDM4E B2RXH2 5/20 0.57
HPGD P15428 4/20 0.57
POLB P06746 4/20 0.57
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
PKM P14618 1/20 0.57
IP6K1 Q92551 1/20 0.52
SMN1; SMN2 Q16637 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
HSD17B10 Q99714 4/20 0.49
NPC1 O15118 1/20 0.49
LMNA P02545 1/20 0.49
TP53 P04637 1/20 0.49
MAPT P10636 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7166496 0.99 PRKDC (0.56) PRKDCPIK3CDPIK3CAPIK3CBPIK3CG
SCHEMBL10995462 0.99 PRKDC (0.56) PRKDCPIK3CDPIK3CAPIK3CBPIK3CG
SCHEMBL10396068 0.88 PRKDC (0.76) PRKDCPIK3CDPIK3CAPIK3CBPIK3CG
SCHEMBL2782693 0.85 PRKDC (0.77) PRKDCPIK3CDPIK3CAPIK3CBPIK3CG
SCHEMBL733038 0.85 ALDH1A1 (0.62) PRKDCPIK3CDPIK3CAPIK3CBPIK3CG
SCHEMBL11300031 0.84 ALDH1A1 (0.81) PRKDCPIK3CDPIK3CAPIK3CBPIK3CG
SCHEMBL14982092 0.84 NPC1 (0.49) PRKDCPIK3CDPIK3CAPIK3CBPIK3CG
SCHEMBL7737344 0.84 PRKDC (0.50) PRKDCPIK3CDPIK3CAPIK3CBPIK3CG
SCHEMBL7724768 0.82 IP6K1 (0.55) PRKDCPIK3CDPIK3CAPIK3CBPIK3CG
SCHEMBL11432002 0.81 HIF1A (0.55) ALDH1A1KDM4EHPGDIP6K1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1323413-B1 Light screening composition comprising a 1,3,5-triazine derivative, a dibenzoylmethane derivative and an amino substituted 2-hydroxybenzophenone derivative L'ORÉAL (FR) 2016-12-21 EP claimed
US-6703002-B2 Synergistically UV-photoprotecting sunscreen compositions comprising camphorsulfonic acid/benzophenone compounds Societe L′Oreal S.A. (FR) 2004-03-09 US claimed
US-6699460-B2 UV-photostabilized sunscreen compositions comprising dibenzoylmethane/triazine/benzophenone compounds SOCIETE L'OREAL S.A. (FR) 2004-03-02 US claimed
US-6699461-B2 UV-photostabilized sunscreen compositions comprising dibenzoylmethane/benzophenone compounds SOCIETE L'OREAL S.A. (FR) 2004-03-02 US claimed
US-6635239-B2 Topically applicable cosmetic/dermatological self-tanning composition with colorations that are more chromatic, are more stable over time, and have good homogeneity SOCIETE L'OREAL S.A. (FR) 2003-10-21 US claimed
US-6627180-B2 Particles having protection factor UV-APPD and an amino substituted 2-hydroxybenzophenone SOCIETE L'OREAL S.A. (FR) 2003-09-30 US claimed
US-6627179-B2 Benzotriazole substituted silicon compound or polymer, dibenzoylmethane derivative and an amino-substituted 2-hydroxybenzophenone SOCIETE L'OREAL S.A. (FR) 2003-09-30 US claimed
US-20030180230-A1 UV-photostabilized sunscreen compositions comprising dibenzoylmethane/triazine/benzophenone compounds SOCIETE L'OREAL S.A. (FR) 2003-09-25 US claimed
US-20030161793-A1 UV-photostabilized sunscreen compositions comprising dibenzoylmethane/benzophenone compounds SOCIETE L'OREAL S.A. (FR) 2003-08-28 US claimed
US-20030161794-A1 Synergistically UV-photoprotecting sunscreen compositions comprising camphorsulfonic acid/benzophenone compounds SOCIETE L'OREAL S.A. (FR) 2003-08-28 US claimed
US-20030157038-A1 SYNERGISTICALLY UV-PHOTOPROTECTING MIXED SUNSCREEN COMPOSITIONS SOCIETE L'OREAL S.A. (FR) 2003-08-21 US claimed
US-20030152532-A1 SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS SOCIETE L'OREAL S.A. (FR) 2003-08-14 US claimed
US-20030129152-A1 STABLE/IMPROVEDLY SELF-TANNING COMPOSITIONS COMPRISING AMINO-SUBSTITUTED 2-HYDROXYBENZOPHENONE COMPOUNDS SOCIETE L'OREAL S.A. (FR) 2003-07-10 US claimed
EP-1323412-A1 Light screening composition comprising a dibenzoylmethane type screening agent and an amino substituted 2-hydroxybenzophenone derivative L'OREAL (FR) 2003-07-02 EP claimed
EP-1323411-A1 Cosmetic sunscreen compositions based on a synergic mixture of screening agents and their uses L'OREAL (FR) 2003-07-02 EP claimed
EP-1323413-A1 Light screening composition comprising a 1,3,5-triazine derivative, a dibenzoylmethane derivative and an amino substituted 2-hydroxybenzophenone derivative L'OREAL (FR) 2003-07-02 EP claimed
EP-1317920-A1 Self-tanning composition comprising an amino-2-hydroxybenzophenone derivative and a self-tanning agent L'OREAL (FR) 2003-06-11 EP claimed
EP-1317919-A1 Cosmetic sunscreen compositions based on synergistic filter mixture and their use l'Oreal SA (FR) 2003-06-11 EP claimed
EP-1317918-A1 Cosmetic sunscreen compositions based on synergistic filter mixture and their use L'OREAL (FR) 2003-06-11 EP claimed
JP-61016966-A None JP disclosed
EP-1317918-B1 Cosmetic sunscreen compositions based on synergistic filter mixture and their use OREAL (FR) 2019-05-01 EP disclosed
EP-1323413-B1 Light screening composition comprising a 1,3,5-triazine derivative, a dibenzoylmethane derivative and an amino substituted 2-hydroxybenzophenone derivative L'ORÉAL (FR) 2016-12-21 EP disclosed
EP-1323412-B1 Light screening composition comprising a dibenzoylmethane type screening agent and an amino substituted 2-hydroxybenzophenone derivative ORÉAL L (FR) 2016-10-19 EP disclosed
EP-2196189-A1 Cosmetic sunscreen compositions based on synergistic filter mixture and their use L'OREAL (FR) 2010-06-16 EP disclosed
US-6703002-B2 Synergistically UV-photoprotecting sunscreen compositions comprising camphorsulfonic acid/benzophenone compounds Societe L′Oreal S.A. (FR) 2004-03-09 US disclosed
US-6699460-B2 UV-photostabilized sunscreen compositions comprising dibenzoylmethane/triazine/benzophenone compounds SOCIETE L'OREAL S.A. (FR) 2004-03-02 US disclosed
US-6699461-B2 UV-photostabilized sunscreen compositions comprising dibenzoylmethane/benzophenone compounds SOCIETE L'OREAL S.A. (FR) 2004-03-02 US disclosed
US-6635239-B2 Topically applicable cosmetic/dermatological self-tanning composition with colorations that are more chromatic, are more stable over time, and have good homogeneity SOCIETE L'OREAL S.A. (FR) 2003-10-21 US disclosed
US-6627180-B2 Particles having protection factor UV-APPD and an amino substituted 2-hydroxybenzophenone SOCIETE L'OREAL S.A. (FR) 2003-09-30 US disclosed
US-6627179-B2 Benzotriazole substituted silicon compound or polymer, dibenzoylmethane derivative and an amino-substituted 2-hydroxybenzophenone SOCIETE L'OREAL S.A. (FR) 2003-09-30 US disclosed
US-20030180230-A1 UV-photostabilized sunscreen compositions comprising dibenzoylmethane/triazine/benzophenone compounds SOCIETE L'OREAL S.A. (FR) 2003-09-25 US disclosed
US-20030161793-A1 UV-photostabilized sunscreen compositions comprising dibenzoylmethane/benzophenone compounds SOCIETE L'OREAL S.A. (FR) 2003-08-28 US disclosed
US-20030161794-A1 Synergistically UV-photoprotecting sunscreen compositions comprising camphorsulfonic acid/benzophenone compounds SOCIETE L'OREAL S.A. (FR) 2003-08-28 US disclosed
US-20030157038-A1 SYNERGISTICALLY UV-PHOTOPROTECTING MIXED SUNSCREEN COMPOSITIONS SOCIETE L'OREAL S.A. (FR) 2003-08-21 US disclosed
US-20030152532-A1 SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS SOCIETE L'OREAL S.A. (FR) 2003-08-14 US disclosed
US-20030129152-A1 STABLE/IMPROVEDLY SELF-TANNING COMPOSITIONS COMPRISING AMINO-SUBSTITUTED 2-HYDROXYBENZOPHENONE COMPOUNDS SOCIETE L'OREAL S.A. (FR) 2003-07-10 US disclosed
EP-1323411-A1 Cosmetic sunscreen compositions based on a synergic mixture of screening agents and their uses L'OREAL (FR) 2003-07-02 EP disclosed
EP-1323412-A1 Light screening composition comprising a dibenzoylmethane type screening agent and an amino substituted 2-hydroxybenzophenone derivative L'OREAL (FR) 2003-07-02 EP disclosed
EP-1323413-A1 Light screening composition comprising a 1,3,5-triazine derivative, a dibenzoylmethane derivative and an amino substituted 2-hydroxybenzophenone derivative L'OREAL (FR) 2003-07-02 EP disclosed
EP-1317919-A1 Cosmetic sunscreen compositions based on synergistic filter mixture and their use l'Oreal SA (FR) 2003-06-11 EP disclosed
EP-1317920-A1 Self-tanning composition comprising an amino-2-hydroxybenzophenone derivative and a self-tanning agent L'OREAL (FR) 2003-06-11 EP disclosed
EP-1317918-A1 Cosmetic sunscreen compositions based on synergistic filter mixture and their use L'OREAL (FR) 2003-06-11 EP disclosed
WO-2001066631-A1 USE OF AMINO-SUBSTITUTED HYDROXYBENZOPHENONES AS LIGHT-STABILITY AGENTS AND STABILIZERS FOR NON-LIVING ORGANIC MATERIAL BASF AKTIENGESELLSCHAFT (DE) 2001-09-13 WO disclosed
US-5149689-A Fluoran color former mixture and use thereof in recording materials CIBA-GEIGY CORPORATION (US) 1992-09-22 US disclosed
EP-0266311-B1 FLUORAN DYE MIXTURE AND ITS USE IN RECORDING MATERIALS CIBA-GEIGY AG (CH) 1992-06-17 EP disclosed
US-5071480-A FLUORAN COLOR FORMER MIXTURE AND USE THEREOF IN RECORDING MATERIALS CIBA-GEIGY CORPORATION (US) 1991-12-10 US disclosed
US-4677203-A Chromogenic fluoran derivatives SHIN NISSO KAKO CO., LTD. (JP) 1987-06-30 US disclosed
US-4639750-A 2-AND/OR 6-PYRIDYLETHYLAMINO-SUBSTITUTED FLUORANS AS COLOR FORMERS FOR DUPLICATIONG AND MARKING SYSTEMS THE HILTON-DAVIS CHEMICAL COMPANY (US) 1987-01-27 US disclosed
US-4594601-A Fluoran compounds HODOGAYA CHEMICAL CO., LTD. (JP) 1986-06-10 US disclosed
JP-S6116966-A PHTHALIDE, ITS PRODUCTION, AND HEAT-SENSITIVE RECORDING PAPER CONTAINING THE SAME AS AN ELECTRODONATIVE COLOR DEVELOPER YAMAMOTO KAGAKU GOSEI KK 1986-01-24 JP disclosed
US-4524373-A Fluoran derivatives as new compounds, process for preparing the same and recording system utilizing the same as colorless chromogenic material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1985-06-18 US disclosed
EP-0110366-A2 Pyridylethylaminofluorans STERLING DRUG INC. (US) 1984-06-13 EP disclosed
US-4447616-A FLUORAN COLOR FORMER INTERMEDIATES STERLING DRUG INC. (US) 1984-05-08 US disclosed
US-4410708-A Chromogenic fluoran derivatives and the preparation and use thereof SHIN NISSO KAKO CO., LTD. (JP) 1983-10-18 US disclosed
EP-0089752-A2 Fluoran derivatives, process for their preparation and their use in recording systems KANZAKI PAPER MANUFACTURING CO., LTD (JP) 1983-09-28 EP disclosed
US-3959571-A PRESSURE OR HEAT SENSITIVE COPYING PAPER SHIN NISSO KAKO CO., LTD. (JA) 1976-05-25 US disclosed
US-3959571-A PRESSURE OR HEAT SENSITIVE COPYING PAPER SHIN NISSO KAKO CO., LTD. (JA) 1976-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030180230-A1 UV-photostabilized sunscreen compositions comprising dibenzoylmethane/triazine/benzophenone compounds DHPS, WEE2, DDT PRKDC 1764/4885PIK3CD 3396/4885PIK3CA 2447/4885
US-20030161793-A1 UV-photostabilized sunscreen compositions comprising dibenzoylmethane/benzophenone compounds HADHB, HADH, NOTUM PRKDC 1870/4885PIK3CD 3023/4885PIK3CA 2070/4885
US-20030161794-A1 Synergistically UV-photoprotecting sunscreen compositions comprising camphorsulfonic acid/benzophenone compounds HADH, HADHB, BCAS2 PRKDC 2061/4885PIK3CD 3756/4885PIK3CA 2279/4885
US-20030129152-A1 STABLE/IMPROVEDLY SELF-TANNING COMPOSITIONS COMPRISING AMINO-SUBSTITUTED 2-HYDROXYBENZOPHENONE COMPOUNDS TYR, MITF, CYP51A1 PRKDC 2797/4885PIK3CD 3949/4885PIK3CA 3409/4885
US-20030157038-A1 SYNERGISTICALLY UV-PHOTOPROTECTING MIXED SUNSCREEN COMPOSITIONS PSAT1, TST, BPTF PRKDC 2087/4885PIK3CD 3736/4885PIK3CA 3307/4885
US-20030152532-A1 SYNERGISTICALLY UV-PHOTOPROTECTING COMPOSITIONS COMPRISING MIXED SCREENING AGENTS HADHB, SDHA, ERCC4 PRKDC 1577/4885PIK3CD 3611/4885PIK3CA 3339/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.