Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11314713 | 0.82 | KDM4E (0.54) | KDM4EGAAALDH1A1HPGDHSD17B10 | |
| SCHEMBL24141126 | 0.82 | KDM4E (0.72) | KDM4EGAAALDH1A1HPGDHSD17B10 | |
| SCHEMBL24140535 | 0.82 | KDM4E (0.73) | KDM4EGAAALDH1A1HPGDHSD17B10 | |
| SCHEMBL11324202 | 0.81 | ALDH1A1 (0.58) | KDM4EALDH1A1HPGDHSD17B10TP53 | |
| SCHEMBL11328183 | 0.79 | ESR1 (0.57) | KDM4EGAAALDH1A1HPGDHSD17B10 | |
| SCHEMBL7260316 | 0.79 | KDM4E (0.56) | KDM4EGAAALDH1A1HPGDHSD17B10 | |
| SCHEMBL11324101 | 0.78 | GRIK1 (0.56) | KDM4EGAAALDH1A1HPGDHSD17B10 | |
| SCHEMBL25876977 | 0.78 | KDM4E (0.67) | KDM4EGAAALDH1A1HPGDHSD17B10 | |
| SCHEMBL10080422 | 0.78 | KDM4E (0.80) | KDM4EGAAALDH1A1HPGDHSD17B10 | |
| SCHEMBL11313561 | 0.77 | KDM4E (0.73) | KDM4EGAAALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4174321-A | POLYMERIC MOLDING MATERIALS | EASTMAN KODAK COMPANY (US) | 1979-11-13 | — | — | US | disclosed |
| US-4127501-A | BENZOXAZOLE, BENZOTHIAZOLE, BENZIMIDAZOLE, BENZOTRIAZOLE OR INDOLE DERIVATIVES | EASTMAN KODAK COMPANY (US) | 1978-11-28 | — | — | US | disclosed |