SCHEMBL11314751

SCHEMBL11314751

CC(=O)NC(CNC(=O)c1ccc2ccccc2c1O)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.49
ALDH1A1 P00352 2/20 0.49
LDHA P00338 1/20 0.48
KMT2A Q03164 6/20 0.47
TDP1 Q9NUW8 1/20 0.47
MEN1 O00255 5/20 0.46
KDM4A O75164 1/20 0.46
CTDSP1 Q9GZU7 1/20 0.46
KDM4C Q9H3R0 1/20 0.46
MAPT P10636 2/20 0.45
LMNA P02545 1/20 0.45
HTT P42858 1/20 0.45
PSEN1 P49768 1/20 0.44
PSEN2 P49810 1/20 0.44
APH1B Q8WW43 1/20 0.44
NCSTN Q92542 1/20 0.44
APH1A Q96BI3 1/20 0.44
PSENEN Q9NZ42 1/20 0.44
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9508883 0.79 MEN1 (0.56) KDM4EALDH1A1LDHAKMT2AMEN1
SCHEMBL11634096 0.77 MTNR1A (0.57) ALDH1A1KMT2ATDP1MAPTLMNA
SCHEMBL590190 0.75 CYP1A1 (0.51) KDM4EALDH1A1LDHAKMT2AMEN1
SCHEMBL11507636 0.74 LDHA (0.62) KDM4EALDH1A1LDHAKMT2AMEN1
SCHEMBL9400432 0.73 EGLN1 (0.66) KDM4ELDHAKMT2AMEN1MAPT
SCHEMBL22975325 0.73 LDHA (0.54) KDM4EALDH1A1LDHAKMT2AMEN1
SCHEMBL4626021 0.72 MEN1 (0.56) KDM4EALDH1A1LDHAKMT2AMEN1
SCHEMBL7192236 0.71 PLK1 (0.66) KDM4EALDH1A1LDHAKMT2AMEN1
SCHEMBL7514107 0.70 HTT (0.64) KDM4ELDHAKMT2AMEN1KDM4A
SCHEMBL10951610 0.69 MEN1 (0.50) KDM4EALDH1A1LDHAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4288532-A Color photographic materials containing cyan color-forming couplers FUJI PHOTO FILM CO., LTD. (JP) 1981-09-08 US disclosed