Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MIF | P14174 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4600026 | 0.94 | GAA (0.54) | GAAALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL20393436 | 0.84 | GAA (0.68) | GAAALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL8340607 | 0.83 | GAA (0.71) | GAAALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL14448733 | 0.82 | ALOX15 (0.48) | GAAALDH1A1LMNAHTTKMT2A | |
| SCHEMBL11702598 | 0.82 | ALDH1A1 (0.47) | GAAALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL30337786 | 0.82 | ALDH1A1 (0.47) | GAAALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL19427462 | 0.81 | ERCC1 (0.51) | GAAALDH1A1LMNAHTTKMT2A | |
| SCHEMBL9677227 | 0.81 | KMT2A (0.59) | GAAKMT2AHSD17B10MAPTHPGD | |
| SCHEMBL7933974 | 0.80 | GAA (0.48) | GAAALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL924084 | 0.80 | KMT2A (0.58) | GAALMNASMN1; SMN2KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4306930-A | INCORPORATING A HYDRAZIDE OR DIHYDRAZIDE AND THEN VULCANIZING IN CONTACT WITH A METAL | CIBA-GEIGY CORPORATION (US) | 1981-12-22 | — | — | US | disclosed |
| US-4077948-A | N-SALICYLIDENE-N*-SALICYLHYDRAZIDES | CIBA-GEIGY CORPORATION (US) | 1978-03-07 | — | — | US | disclosed |