Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11314943 | 0.89 | ABL1 (0.39) | DRD2SIGMAR1MAPTSMN1; SMN2TP53 | |
| SCHEMBL11322050 | 0.86 | MAOB (0.42) | NPC1RAB9AHDAC4HDAC8NPY5R | |
| SCHEMBL11774943 | 0.85 | PTPN1 (0.49) | PTPN1DRD2SIGMAR1MAPTNPC1 | |
| SCHEMBL29390919 | 0.85 | CFTR (0.44) | DRD2SIGMAR1MAPTSMN1; SMN2TP53 | |
| SCHEMBL37303 | 0.85 | CFTR (0.44) | DRD2SIGMAR1MAPTSMN1; SMN2TP53 | |
| SCHEMBL6341038 | 0.85 | CFTR (0.44) | DRD2SIGMAR1MAPTSMN1; SMN2TP53 | |
| Methyl Alcohol SCHEMBL27955397 | 0.84 | SIGMAR1 (0.42) | DRD2SIGMAR1MAPTSMN1; SMN2TP53 | |
| SCHEMBL11314758 | 0.84 | PTPRC (0.39) | DRD2SIGMAR1MAPTNPC1RAB9A | |
| Ammonia Solution, Strong SCHEMBL13731210 | 0.84 | CFTR (0.42) | DRD2SIGMAR1MAPTSMN1; SMN2TP53 | |
| SCHEMBL11321765 | 0.83 | HDAC4 (0.44) | MAPTSMN1; SMN2TSHRHDAC4HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4276049-A | Method for the determination of an amino or aminosulphonic acid | HOFFMANN-LA ROCHE INC. (US) | 1981-06-30 | — | — | US | disclosed |