SCHEMBL37303

SCHEMBL37303

O=C1OC2(OC=C(c3ccccc3)C2=O)c2ccccc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CFTR P13569 1/20 0.44
GOPC Q9HD26 1/20 0.44
SIGMAR1 Q99720 10/20 0.42
DRD2 P14416 6/20 0.42
GAA P10253 2/20 0.38
NPSR1 Q6W5P4 2/20 0.38
PKM P14618 1/20 0.37
HSP90AA1 P07900 1/20 0.37
GRIN2D O15399 1/20 0.36
GRIN3B O60391 1/20 0.36
GRIN1 Q05586 1/20 0.36
GRIN2A Q12879 1/20 0.36
GRIN2B Q13224 1/20 0.36
GRIN2C Q14957 1/20 0.36
GRIN3A Q8TCU5 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
CYP3A4 P08684 2/20 0.36
POLB P06746 1/20 0.36
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29390919 1.00 CFTR (0.44) CFTRGOPCSIGMAR1DRD2GAA
SCHEMBL6341038 1.00 CFTR (0.44) CFTRGOPCSIGMAR1DRD2GAA
Ammonia Solution, Strong SCHEMBL13731210 0.98 CFTR (0.42) CFTRGOPCSIGMAR1DRD2GAA
Methyl Alcohol SCHEMBL27955397 0.96 SIGMAR1 (0.42) CFTRGOPCSIGMAR1DRD2GAA
Acetone SCHEMBL3494828 0.93 SIGMAR1 (0.40) CFTRGOPCSIGMAR1DRD2GAA
Alcohol SCHEMBL6307137 0.92 SIGMAR1 (0.42) CFTRGOPCSIGMAR1DRD2GAA
Isothiocyanate SCHEMBL16059997 0.92 CFTR (0.38) CFTRGOPCSIGMAR1DRD2GAA
SCHEMBL11314758 0.90 PTPRC (0.39) CFTRGOPCSIGMAR1DRD2GAA
SCHEMBL11312792 0.88 ALDH1A1 (0.39) CFTRGOPCSIGMAR1DRD2NPSR1
Allylamine SCHEMBL11236327 0.88 SIGMAR1 (0.42) CFTRGOPCSIGMAR1DRD2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 23797 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4748304-A2 SYSTEM AND METHOD FOR IDENTIFYING BLOOD VESSELS DURING FLUORESCENCE IMAGING Perfusion Tech ApS (DK) 2026-05-27 EP claimed
WO-2026099761-A1 PEPTIDES SALEM YAHYA AHMED (EG) 2026-05-15 WO claimed
US-20260096736-A1 SYSTEM AND METHOD FOR IDENTIFYING AN ABNORMAL PERFUSION PATTERN PERFUSION TECH APS (DK) 2026-04-09 US claimed
US-20260069175-A1 SAMPLE-TO-ANSWER DIAGNOSTIC SYSTEM FOR THE DETECTION OF CIRCULATING HISTONES IN WHOLE BLOOD UNIV MARYLAND (US) 2026-03-12 US claimed
US-12551149-B2 Sample-to-answer diagnostic system for the detection of circulating histones in whole blood UNIVERSITY OF MARYLAND, COLLEGE PARK (US) 2026-02-17 US claimed
US-12518390-B2 Methods and systems for characterizing tissue of a subject STRYKER CORPORATION (US) 2026-01-06 US claimed
EP-4076149-B1 SYSTEM AND COMPUTER PROGRAM FOR IDENTIFYING BLOOD VESSELS DURING FLUORESCENCE IMAGING PERFUSION TECH APS (DK) 2025-12-24 EP claimed
US-20250341022-A1 NANOCRYSTALLINE STRUCTURE SUBSTRATE TOKUSHIMA UNIVERSITY (JP) 2025-11-06 US claimed
EP-4643890-A1 TISSUE-MARKING AGENT CONTAINING FLUORESCENT DYE-LABELLED PARTICLES National Institute for Materials Science (JP) 2025-11-05 EP claimed
US-12440115-B2 System and method for identifying an abnormal perfusion pattern PERFUSION TECH APS (DK) 2025-10-14 US claimed
US-4345027-A Fluorometric method of quantitative cell mutagenesis THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1982-08-17 US claimed
WO-1982002601-A1 SOLID PHASE SYSTEM FOR LIGAND ASSAY AMERICAN HOSPITAL SUPPLY CORP (US) 1982-08-05 WO claimed
US-4342748-A ISOLATED FROM ANIMAL BRAINS OR HUMAN URINE BY SOLVENT EXTRACTION A PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 1982-08-03 US claimed
US-4326008-A CROSSLINKED ACRYLIC POLYMERS CONTAINING A FLUORESCENT COMONOMER CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1982-04-20 US claimed
US-4276049-A Method for the determination of an amino or aminosulphonic acid HOFFMANN-LA ROCHE INC. (US) 1981-06-30 US claimed
US-4272505-A Competitive binding analysis by fluorescence TECHNICON INSTRUMENTS CORPORATION (US) 1981-06-09 US claimed
US-4264329-A IN UNDERGROUND RESERVOIRS USING A METAL CHELATE HAVING A FUNCTIONAL GROUP WHICH REACTS WITH A FLUOROGENIC AGENT CITIES SERVICE COMPANY (US) 1981-04-28 US claimed
EP-0011107-A1 Method for the determination of an amino acid or an amino sulfonic acid F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1980-05-28 EP claimed
US-4203967-A Diagnostic test for malabsorption HOFFMANN-LA ROCHE INC. (US) 1980-05-20 US claimed
US-4160818-A Fluorimetric immunoassay for diphenylhydantoin TECHNICON INSTRUMENTS CORPORATION (US) 1979-07-10 US claimed