Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 2/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | CD69 | Q07108 | 1/20 | 0.42 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11308419 | 0.93 | KDM4E (0.46) | KDM4ETSHRALOX15HSD17B10HPGD | |
| SCHEMBL11314969 | 0.86 | KDM4E (0.47) | KDM4ETSHRALOX15HSD17B10HPGD | |
| SCHEMBL11314670 | 0.83 | CD69 (0.45) | TSHRHSD17B10HPGDSMN1; SMN2PGR | |
| SCHEMBL11315111 | 0.80 | PGR (0.39) | KDM4ETSHRALOX15HSD17B10PGR | |
| SCHEMBL11308421 | 0.80 | KDM4E (0.44) | KDM4ETSHRALOX15HSD17B10HPGD | |
| SCHEMBL11305126 | 0.80 | GLA (0.42) | KDM4ETSHRSMN1; SMN2PGRELANE | |
| SCHEMBL11313746 | 0.75 | KDM4E (0.45) | KDM4ETSHRALOX15HSD17B10HPGD | |
| SCHEMBL10926369 | 0.74 | KDM4E (0.79) | KDM4ETSHRALOX15HSD17B10HPGD | |
| SCHEMBL17287096 | 0.73 | PGR (0.44) | TSHRALOX15HSD17B10SMN1; SMN2PGR | |
| SCHEMBL10687428 | 0.72 | NR1H4 (0.52) | TSHRHSD17B10PGRPTGDR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4272550-A | Omega-[4-(polyfluoro-2-hydroxy-2-propyl)-2,3,6-substituted-phenoxy and phenylthio]alkanoic acids and compounds related thereto | SCHERING CORPORATION (US) | 1981-06-09 | — | — | US | disclosed |
| US-4199597-A | Omega-(4-polyfluoro-2-hydroxy-2-propyl)-2,3,6-substituted-phenoxy and phenylthio)alkanoic acids and compounds related thereto | SCHERING CORPORATION (US) | 1980-04-22 | — | — | US | disclosed |