Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD69 | Q07108 | 2/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 4/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MLYCD | O95822 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PTPRB | P23467 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11308419 | 0.89 | KDM4E (0.46) | CD69ELANEPPARDPPARASMN1; SMN2 | |
| SCHEMBL11308094 | 0.86 | PTGDR2 (0.39) | PPARDPPARAPTPN1SMN1; SMN2MLYCD | |
| SCHEMBL11314673 | 0.84 | PTPN1 (0.44) | CD69ELANEPPARDPPARAPTPN1 | |
| SCHEMBL11307536 | 0.84 | MMP1 (0.42) | PPARDPPARAMLYCDNR1H2NR1H3 | |
| SCHEMBL11314964 | 0.83 | KDM4E (0.49) | CD69ELANESMN1; SMN2TSHRPGR | |
| SCHEMBL11305131 | 0.83 | LMNA (0.45) | MLYCDHSD17B10 | |
| SCHEMBL11307463 | 0.83 | MLYCD (0.46) | SMN1; SMN2MLYCDNR1H2NR1H3PGR | |
| SCHEMBL11306601 | 0.83 | CD69 (0.44) | CD69ELANEPPARDPPARAPTPN1 | |
| SCHEMBL11307507 | 0.81 | CD69 (0.43) | CD69ELANEPPARDPPARAPTPN1 | |
| SCHEMBL11306603 | 0.80 | PPARD (0.42) | CD69ELANEPPARDPPARAPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4199597-A | Omega-(4-polyfluoro-2-hydroxy-2-propyl)-2,3,6-substituted-phenoxy and phenylthio)alkanoic acids and compounds related thereto | SCHERING CORPORATION (US) | 1980-04-22 | — | — | US | claimed |
| US-4272550-A | Omega-[4-(polyfluoro-2-hydroxy-2-propyl)-2,3,6-substituted-phenoxy and phenylthio]alkanoic acids and compounds related thereto | SCHERING CORPORATION (US) | 1981-06-09 | — | — | US | disclosed |
| US-4199597-A | Omega-(4-polyfluoro-2-hydroxy-2-propyl)-2,3,6-substituted-phenoxy and phenylthio)alkanoic acids and compounds related thereto | SCHERING CORPORATION (US) | 1980-04-22 | — | — | US | disclosed |