Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 2/20 | 0.63 |
| ▸ | PGR | P06401 | 1/20 | 0.63 |
| ▸ | PPARG | P37231 | 1/20 | 0.63 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.63 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.63 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | SLC15A2 | Q16348 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11321802 | 0.91 | NR1I2 (0.54) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL11307933 | 0.90 | PTGS1 (0.76) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL8883027 | 0.86 | PTGS1 (0.82) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL11215612 | 0.86 | PTGS1 (0.82) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL11142576 | 0.84 | ALDH1A1 (0.60) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL11142573 | 0.84 | ALDH1A1 (0.60) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL11529683 | 0.84 | PTGS1 (0.70) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL11219439 | 0.84 | PTGS1 (0.65) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL11858543 | 0.83 | ALDH1A1 (0.59) | NR1I2PGRPPARGSLC22A6SLC22A8 | |
| SCHEMBL11220098 | 0.83 | PTGS1 (0.62) | NR1I2PGRPPARGSLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4248868-A | FOR TREATING SYSTEMIC INFECTIONS BY GRAMPOSITIVE AND GRAM NEGATIVE BACTERIA | CIBA-GEIGY CORPORATION (US) | 1981-02-03 | — | — | US | claimed |
| US-4248868-A | FOR TREATING SYSTEMIC INFECTIONS BY GRAMPOSITIVE AND GRAM NEGATIVE BACTERIA | CIBA-GEIGY CORPORATION (US) | 1981-02-03 | — | — | US | disclosed |