Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11311778 | 0.89 | MEN1 (0.52) | RAB9ANPC1SMN1; SMN2KDM4EESR1 | |
| SCHEMBL11314927 | 0.84 | KMT2A (0.70) | RAB9ANPC1SMN1; SMN2KDM4EESR1 | |
| SCHEMBL11309845 | 0.81 | MEN1 (0.46) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL11306216 | 0.79 | ALDH1A1 (0.47) | SMN1; SMN2KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL11309066 | 0.78 | POLB (0.53) | RAB9ANPC1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL11694836 | 0.76 | TP53 (0.57) | RAB9ANPC1SMN1; SMN2KDM4EESR1 | |
| SCHEMBL11693812 | 0.76 | HDAC1 (0.53) | RAB9ANPC1SMN1; SMN2KDM4EESR1 | |
| SCHEMBL3462645 | 0.74 | KMT2A (0.59) | RAB9ANPC1SMN1; SMN2KDM4EESR1 | |
| SCHEMBL6809719 | 0.73 | RAB9A (0.64) | RAB9ANPC1SMN1; SMN2KDM4EESR1 | |
| SCHEMBL11308885 | 0.73 | MEN1 (0.74) | RAB9ANPC1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4263205-A | FOR COLORING POLYMERS, LACQUERS | CIBA-GEIGY CORPORATION (US) | 1981-04-21 | — | — | US | disclosed |
| EP-0006154-A1 | Monoazo pigments and their use in colouring high molecular-weight organic material | CIBA-GEIGY AG (CH) | 1980-01-09 | — | — | EP | disclosed |
| US-4062838-A | LACQUERS, PRINTING INKS, YELLOW TO ORANGE | CIBA-GEIGY CORPORATION (US) | 1977-12-13 | — | — | US | disclosed |